M. Chandrasekaran, Venugopalan Venkatesalu, G. Adaikala Raj, S. Krishnamoorthy, Antibacterial Activity of Ulva fasciata against Multidrug Resistant Bacterial Strains, ILNS Volume 19, International Letters of Natural Sciences (Volume 19)
https://www.scipress.com/ILNS.19.40
Abstract:
    The present study was conducted to evaluate the antibacterial activity of different organic solvent increasing polarity <i>viz</i>., hexane, chloroform, ethyl acetate, acetone and methanol extracts of <i>Ulva fasciata</i> (Chlorophyceae) were collected from Kanniyakummari, Gulf of Mannar biosphere Reserve, Tamilnadu, India. Marine green algae extracts of<i> U. fasciata</i> against multi-drug resistant standard and clinical bacterial strains <i>viz., Bacillus subtilis, Streptococcus pyogenes, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Salmonella typhimurium, Vibrio cholerae, Shigella flexneri, Proteus mirabilis and P. vulgaris</i>. The ethyl acetate extracts of <i>U. fasciata</i> showed highest antibacterial activity against all the bacterial strains tested. The mean zone of inhibition produced by the extracts in disc diffusion assays were ranged from 7.1 mm to 15.0 mm. The Minimum Inhibitory Concentrations (MIC) were between 125 μg/ml and 500 μg/ml, while the Minimum Bactericidal Concentrations (MBC) were between 250 μg/ml and 1000 μg/ml. The highest mean of zone inhibition (15.0 mm) and lowest MIC (125 μg/ml) and MBC (250 μg/ml) values were observed in ethyl acetate extract of <i>U. fasciata</i> against <i>B. subtilis</i>. The ethyl acetate extract of the <i>U. fasciata</i> showed the presence of phytochemicals, terpenoids, tannins and phenolic compounds in<i> U. fasciata</i> than the other solvents extracts. The present results of the ethyl acetate extract of <i>U. fasciata</i> can be used as an antibacterial substance for the treatment of multi drug resistant bacterial infections
Keywords:
    Antibacterial Activity, MDR Bacterial Strains, <i>Ulva fasciata</i>