Fadia Al Haj Hussien, Mohammad Keshe, Khaled Alzobar, Joumaa Merza, Ayman Karam, Synthesis and Nitration of 7-Hydroxy-4-Methyl Coumarin via Pechmann Condensation Using Eco-Friendly Medias, ILCPA Volume 69, International Letters of Chemistry, Physics and Astronomy (Volume 69)
    A nitro coumarin derivatives has been synthesized via nitration of 7-hydroxy-4-methyl coumarin wich was synthesized via Pechmann condensation resorcinol with a β-ketoester using Amberlyst-15 as a green and efficient catalyst and by caring out the reaction of resorcinol and ethyl acetoacetate (with 1: 1 mol ratio) in the presence of 0.2 g of Amberlyst-15 at 110°C under solvent-free conditions. These nitro coumarin derivatives have biological activity and momentousness in the industrial fields. The purified products were measured the melting points and characterized by spectral methods: FT-IR, <sup>1</sup>H-NMR , <sup>13</sup>C-NMR.
    Coumarin, Eco-Friendly Medias, Pechmann Condensation