Dipti L. Namera, Jaynt B. Rathod, Rupali H. Maheta, Umed C. Bhoya, Microwave Assisted Synthesis of 2,5-Distyryl-1,3,4-Oxadiazole Derivatives as Anti Microbial Agents, Volume 29, International Letters of Chemistry, Physics and Astronomy (Volume 29)
https://www.scipress.com/ILCPA.29.46
Abstract:
    A new series of 2,5-distyryl-1,3,4-oxadiazoles derivatives have been synthesized from cinnamic hydrazide on reaction with various cinnamic acid derivatives. The structures of synthesized compounds have been elucidated by spectral studies like IR, <sup>1</sup>HNMR, Mass and also Elemental Analysis. Furthermore, all synthesized compounds were screened for I<i>n Vitro</i> anti microbial activity against the gram positive (<i>Staphylococcus aureus</i>, <i>Pseudomonas aeruginosa</i>) and gram negative (<i>Escherichia coli</i>) bacterial strain. In which some the compounds show potential inhibition against the test organisms.
Keywords:
    Antimicrobial Activity, Substituted 1,3,4-Oxadiazoles, Substituted Cinnamic Acid