Ankur A. Kaneria, Nilesh M. Thumar, Kartik D. Ladva, Milan S. Vadodaria, Synthesis, Characterization and Antimicrobial Activities of some Novel 3-(4-Bromobenzyl)-5-(Thiophen-2-yl)-4H-1,2,4-Triazol Derivatives, ILCPA Volume 68, International Letters of Chemistry, Physics and Astronomy (Volume 68)
https://www.scipress.com/ILCPA.68.10
Abstract:
    A convenient and promising synthesis of 4-(alkyl/aryl)- 3-(4-bromobenzyl)-5-(thiophen-2-yl)-4H-1,2,4-triazol was carried out by the reaction of 2-(4-bromobenzyl)-5-(thiophen-2-yl)-1,3,4-oxadiazole with different aliphatic/aromatic primary amine without any solvent. The newly synthesized compound were characterized by <sup>1</sup>H NMR, IR and Mass spectroscopy and also screened for their antimicrobial activity against various strains of bacteria and fungi.
Keywords:
    3,4,5-Trisubstituted-1,2,4-Triazol, Antimicrobial Activities, Thiophene Derivatives, Triazole Derivatives