G. Thirunarayanan, S. Dineshkumar, R. Arulkumaran, R. Sundararajan, D. Kamalakkannan, R. Suresh, S.P. Sakthinathan, V. Manikandan, Ganesan Vanangamudi, Synthesis, Spectral Studies, Pharmacological and Insect Antifeedant Activities of some (E)-1-(2-(2-Benzyloxy-3-Methacrylate))-1-Naphthyl Enones, ILCPA Volume 57, International Letters of Chemistry, Physics and Astronomy (Volume 57)
https://www.scipress.com/ILCPA.57.51
Abstract:
    Totally twelve title compounds have been synthesized by Claisen-Schmidt condensation of (<i>E</i>)-methyl 2-(2-(((1-acetylnaphthalen-2-yl) oxy) methyl) phenyl)-3-methoxy acrylate and substituted benzaldehydes in presence of catalytic quantity of LiOH.H<sub>2</sub>O catalyst under stirring in room temperature. The yields of the compounds are more than 92%. The synthesized titled compounds were characterized by their physical constants, IR, NMR and Mass spectral data. The spectral data such as infrared ν CO<i><sub>s-cis</sub></i>, <i><sub>s-trans</sub></i>, CO<sub>ester</sub>, NMR chemical shifts (δ, ppm) of H<sub>α</sub>, H<sub>β</sub>, C<sub>α</sub>, C<sub>β</sub>, CO of enone moiety, H<sub>βʹ</sub> and CO of acrylate moieties have been correlated with Hammett substituent constants, F and R parameters. The antimicrobial, antioxidant and insect antifeedant activities of all synthesized compounds have been evaluated using corresponding bacterial and fungal strains, DPPH radical scavenging and Disc diffusion bio-assay of 4<sup>th</sup> instar larvae <i>Achoea Janata L</i> with castor-leaf discs.
Keywords:
    (E)- 2-Benzyloxy-(3-Methoxy Acrylate)-1-Naphthyl Enones, Antimicrobial Activity, Antioxidant Activity, Hammett Equation, Insect Antifeedant Activity