V.V. Bhuva, V.N. Bhadani, H.D. Purohit, Dipak M. Purohit, Synthesis and Antimicrobial Screening of 2"-Amino-4"-[2-(4'-Chlorophenyl)-6-Methyl Imidazo[1, 2-a]Pyridine -3-yl]-6"-Aryl-4"-H-Pyran-3"-Carbonitrile, ILCPA Volume 49, International Letters of Chemistry, Physics and Astronomy (Volume 49)
https://www.scipress.com/ILCPA.49.149
Abstract:
    3-Cyano-4,6-disubstituted 4H-pyrans are endowed with a variety of pharmacodynamic activities Looking to the interesting properties of cyanopyrans, it was considered worthwhile to synthesis some new 2"-amino-4"-[2-(4'-chlorophenyl) -6-methyl imidazo [1,2-a] pyridin-3-yl]-6"-aryl-4"-H-pyran-3"- carbonitrile ( 4a-4l ) have been synthesized. The products have been assayed for their biological activity against Gram +ve, Gram –ve bacteria and fungi. Some of the products showed moderate activity in concentration 50μg/mL. The structures of the products have been elucidated by IR, <sup>1</sup>H-NMR, Mass spectral data, elemental analysis and thin layer chromatography.<i>Keyw</i> <i>ords</i> <i>:</i> Cyanopyrans; antibacterial activity; antifungal activity
Keywords:
    Antibacterial Activity, Antifungal Activity, Cyanopyrans