G.R. Patel, J.J. Maru, Rakesh Yadav, Antimicrobial Screening of Synthesized some Novel Azomethines via Organic Base, Volume 43, International Letters of Chemistry, Physics and Astronomy (Volume 43)
https://www.scipress.com/ILCPA.43.26
Abstract:
    The author has synthesized azomethines in which carbonyl group is replaced by amine of acid hydrazides. The intermediates were prepared by using 2-mercapto benzimidazole with N-(4-Acetyl-phenyl)-2-chloro-acetamide in the presence of K2CO3. The Resulted product was further treated with different substituted of acid hydrazide in ethanol to yield the titled compounds using a catalytic amount of acetic acid. New products were examined for their antibacterial effects against Gram-positive and Gram-negative strains and antifungal were highly potent with lowest MIC Values. The structural assignments of the new products were done on the basis of FT-IR, NMR, Mass spectroscopy and elemental analysis.
Keywords:
    Acid Hydrazide, Antimicrobial Activity, Azomethine, Benzimidazole