Salmonella specie were isolated from Nworie River and then tested against several antibiotics to include; Gentamycin, Streptomycin, Amoxycillin, Kanamycin, Oxacillin, Ofloxacin, Imipenem, Ciprofloxacin, Aztreonam and Ceftazidime. Salmonella isolates obtained from the river were resistant to at least three different antibiotics. All isolates were resistant to Amoxycillin, Oxacillin and Iminipem showing a 100% resistant rate, while showing sensitivity to Ciprofloxacin, Aztreonam, Gentamycin, Ceftazidime, Kanamycin, Streptomycin, and Ofloxacin at sensitivity rates of 71.4%, 7.1%, 77.1%, 11.4%, 44.3%, 48.6% and 78.6% respectively. The antibiotic-resistant Salmonella species were further tested against the aqueous, ethanol and acetone extracts of Vernonia amygdalina leaf, stem and roots to assess their antibacterial potential at a concentration of 100mg/ml. Aqueous extracts of the leaf, stem and roots showed no activity against antibiotic resistant Salmonella isolate, while the ethanol and acetone extracts showed activity rates of 20% and 17% for roots, 14.3% and 12.9% for stem, and, 15.7% and 11.4% for leaf. The results from this study further confirms the antibacterial potentials of Vernonia amygdalina against antibiotic-resistant bacterial isolates.
International Letters of Natural Sciences (Volume 56)
C. I. Chikwendu et al., "Antibacterial Potentials of Vernonia amygdalina against Antibiotic-Resistant Salmonella Specie Isolated from Nworie River, Imo State, Nigeria", International Letters of Natural Sciences, Vol. 56, pp. 82-89, 2016