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Phytochemistry and Antimicrobial Property of Fruits of Chrysophyllum albidum against Selected Clinical Isolates

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Abstract:

The antimicrobial activity of methanolic and aqueous extracts of Chrysophyllum albidum fruits was investigated against clinical isolates (Staphylococcus aureus, Escherichia coli, Klebsiella pneumonia and Candida albicans). Qualitative phytochemistry of the plant indicated that the plant contained Flavonoids, Steroids, Alkaloids, Tannin, Anthraquinone and Cardiac glycosides while Saponins were reported absent. The maximum activity of the aqueous extracts in the test isolates was observed on Staphylococcus aureus, which showed clear zones with diameters of 24.0mm, 20.0mm and 16.5mm at concentrations of 100mg/ml, 50mg/ml and 25mg/ml respectively while it had low activity on Klebsiella pneumonia, with clear zones of inhibition of 15.0mm, 12.0mm and 10.5mm at same concentrations. On the other hand, Methanolic extracts activity on Staphylococcus aureus produced clear zones of 21.0mm, 17.5mm and 12.0mm at concentrations of 200mg/ml, 100mg/ml and 50mg/ml respectively as its best activity while the it had least observed activity on Klebsiella pneumonia with clear zones of 14.0mm, 11.5mm and 10.5mm at same concentrations. The aqueous extracts had greater activity than the methanolic extracts at same concentrations. Therefore, the fruit of the plant can be a good source of remedy in phytomedicine.

Info:

Periodical:
International Letters of Natural Sciences (Volume 55)
Pages:
44-51
Citation:
S. A. Adeleye et al., "Phytochemistry and Antimicrobial Property of Fruits of Chrysophyllum albidum against Selected Clinical Isolates", International Letters of Natural Sciences, Vol. 55, pp. 44-51, 2016
Online since:
Jun 2016
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[1] Okorondu S. I., Adeleye, S. A. Okorondu, M. M. O. Review on medicinal plants. Nigerian journal of Microbiology, 29(2015) 3167-3183.

[2] Petrovska, B.B. History review of medicinal plants' usage. Pharmacognosy Review. 6 (11) (2012) 1-5.

[3] Iwu, M.M., Duncan, A.R. and Okunji, C.O. New Antimicrobials of plant origin. In Janick, J. (ed) Perspectives in New crops and New uses. ASHS Press, Alexandria, V. A, 1999, Pp 457-462.

[4] Asaolu, M.F. Chemical composition and phytochemical screening of the seeds of Garcinia kola. Pakistan Journal of Science and industrial research, 46(2003) 145-147.

[5] Ciulei, I. Practical Manuals on the Industrial Utilization of Medicinal and Aromatic plants, University of Bucharest, Romania (1964).

[6] Chitravadivu, C., Manian, S. and Kalachelvi, K. Qualitative analysis of Selected Medicinal Plants, Tamilnadu, India. Middle East J. Sci. Res., 4(2009) 144-146.

[7] AOAC. Official Methods of Analysis. Association of Official Analytical Chemists, 15th Edn., Washington D.C., USA (2010).

[8] Buchanan, R. E. and Gibbon, N. E. . Bergey's Manual of Determinative Bacteriology. 8th ed. The Williams and Wilkin's Co. Baltimore, 1984, pp.1246-1249.

[9] Cheesbrough, M. District Laboratory Practise in Tropical Countries Part 2. Cambridge University Press, Cambridge, United Kingdom, 2000, pp.38-219.

[10] Duyilemi, O. P and Lawal, I.O. Antibacterial activity and phytochemical screening of Chrysophyllum albidum leaves. As. J. Food Ag-Ind. Special issue. (2009) S75-S79.

[11] Orijajogun, O.J., Olajide, O.O., Fatokun, A.O., Orishadipe, A.T. and Batari, M.L. The Preliminary Chemical Constituents and Free Radical Scavanging Activities of The Exocarp of The Fruit Extract of African Star Apple (Chrysophyllum albidum G. Don). IJRPS, 3(3) (2013).

[12] Spencer, A.L.R., Spencer, J.F.T. Public Health Microbiology: Methods and Protocols. Human Press Inc. New Jersey, 2004, pp.325-327.

[13] Kamba, A.S. and Hassan, L.G. Phytochemical screening and antimicrobial activities of African star Apple (Chrysophyllum albidum) leaves, stem against some pathogenic microorganism. Int. J. of Pharm. Frontier Research. 1(2) (2011) 119-129.

[14] Aboaba, O.O., Smith, S.T., Olide, F. O. Antimicrobial effect of Edible plant Extract on Escherichia. Coli, 0157: H7. Pak.J. Nutr. 5(4) (2006) 325-327.

[15] Adewusi, H.A. The African star apple Chrysophyllum albidum indigenous knowledge from Ibadan, Southwest Nigeria. In proceedings of a National worksop on the potentials of the star apple in Nigeria, 1997, pp.25-33.

[16] Okoli, B.J. and Okere, O.S. Antimicrobial activity of the phytochemical constituents of Chrysophyllum albidum G. Don Holl (African star apple) plant. Journal of Research in National development, 8(1) (2010) 11-16.

[17] Ajetunmobi, A. O. and Towolawi, G. A. Phytochemical Analysis and Antimicrobial Effect of Chrysophyllum albidum Leave Extract On Gastrointestinal Tract Pathogenic Bacteria and Fungi in Human. IOSR Journal of Applied Chemistry (IOSR-JAC). 7 (1) (2014).

[18] Rios, J.L. and Recio, M.C. Medicinal plants and antimicrobial activity. Journal of Ethnopharmacology, 100(2005) 80-84.

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