Respiratory Surveillance and Ca2+-ATPase Enzyme Activity Studies of Clarias gariepinus Exposed to Acute Toxicity of Cyanide

Oseni, Kadiri

doi:10.18052/www.scipress.com/ILNS.50.62

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Respiratory Surveillance and Ca²⁺-ATPase Enzyme Activity Studies of Clarias gariepinus Exposed to Acute Toxicity of Cyanide

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Abstract:

Potassium cyanide, a highly contaminating and toxic aquatic ecosystems pollutant was investigated for acute toxicity on the freshwater fish Clarias gariepinus. Its effect on the Ca²⁺ -ATPase activities in the liver, gills, muscle and intestinal tissues and oxygen consumption index was studied. Short-term toxicity test was carried out by static renewal bioassay test over a 96 h period using a lethal concentration (LC₅₀) value of 0.361mg/mL. Potassium cyanide was highly toxic to the animal tested. Results reveal that normal respiratory activity (O₂consumption) of the fish was significantly affected and there was significant decreased in the Ca²⁺ - ATPase activities at the end of exposure periods (24, 48, 72 and 96 h). Correlation analysis reveals a strong relationship between oxygen consumption index and ATPase enzyme activity of Clarias gariepinus exposed to the toxicant. This study reflects the toxic effect of potassium cyanide to the freshwater fish, Clarias gariepinus and suggestion on the possible application of Ca²⁺ -ATPase activities and oxygen consumption index as possible biomarkers for early detection of cyanide poisoning in aquatic bodies.

Info:

Periodical:

International Letters of Natural Sciences (Volume 50)

Pages:

62-69

DOI:

https://doi.org/10.18052/www.scipress.com/ILNS.50.62

Citation:

K. Oseni, "Respiratory Surveillance and Ca²⁺-ATPase Enzyme Activity Studies of Clarias gariepinus Exposed to Acute Toxicity of Cyanide", International Letters of Natural Sciences, Vol. 50, pp. 62-69, 2016

Online since:

January 2016

Authors:

Kadiri Oseni

Keywords:

Ca²⁺-ATPase, Catfish, Cyanide, LC₅₀, Toxicity

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Open Access

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Creative Commons Attribution 4.0 International License

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