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Respiratory Surveillance and Ca2+-ATPase Enzyme Activity Studies of Clarias gariepinus Exposed to Acute Toxicity of Cyanide

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Abstract:

Potassium cyanide, a highly contaminating and toxic aquatic ecosystems pollutant was investigated for acute toxicity on the freshwater fish Clarias gariepinus. Its effect on the Ca2+ -ATPase activities in the liver, gills, muscle and intestinal tissues and oxygen consumption index was studied. Short-term toxicity test was carried out by static renewal bioassay test over a 96 h period using a lethal concentration (LC50) value of 0.361mg/mL. Potassium cyanide was highly toxic to the animal tested. Results reveal that normal respiratory activity (O2 consumption) of the fish was significantly affected and there was significant decreased in the Ca2+ - ATPase activities at the end of exposure periods (24, 48, 72 and 96 h). Correlation analysis reveals a strong relationship between oxygen consumption index and ATPase enzyme activity of Clarias gariepinus exposed to the toxicant. This study reflects the toxic effect of potassium cyanide to the freshwater fish, Clarias gariepinus and suggestion on the possible application of Ca2+ -ATPase activities and oxygen consumption index as possible biomarkers for early detection of cyanide poisoning in aquatic bodies.

Info:

Periodical:
International Letters of Natural Sciences (Volume 50)
Pages:
62-69
DOI:
https://doi.org/10.18052/www.scipress.com/ILNS.50.62
Citation:
K. Oseni "Respiratory Surveillance and Ca2+-ATPase Enzyme Activity Studies of Clarias gariepinus Exposed to Acute Toxicity of Cyanide", International Letters of Natural Sciences, Vol. 50, pp. 62-69, 2016
Online since:
Jan 2016
Authors:
Kadiri Oseni
Keywords:
Ca2+-ATPase, Catfish, Cyanide, LC50, Toxicity
Export:
RIS, BibTeX, Text
Distribution:
Open Access

Creative Commons License
This work is licensed under a
Creative Commons Attribution 4.0 International License

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