Antimycotic activity of Petroleum ether and 98% methanolic young leaf soxhlet extract of Solanum nigrum (Solanaceae) was evaluated against dermatophytic fungi namely, Trichophyton rubrum, Trichophyton tonsurans, Trichophyton mentagrophytes, Microsporium gypseum,Candida albicans, and bacteria like, Staphylococcus aureus, Psudomonas aeruginosa, Bacillus subtilis, Escherichia coli. The maximum activity was observed in interpolar methanolic extract when compared to low polar petroleum ether extract. The minimum inhibitory concentration, minimum fungicidal concentration and minimum bactericidal concentration were determined against all the test strains. This study provides a basis for the isolation and purification of anti-dermatophytic compounds from the young leaves of S. nigrum.
International Letters of Natural Sciences (Volume 31)
S. P. Shivakumar and G.M. Vidyasagar, "Antimycotic Activity of Low Polar Petroleum Ether and Interpolar Methanolic Young Leaf Extracts of Solanum nigrum L.", International Letters of Natural Sciences, Vol. 31, pp. 47-56, 2015