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L-Asparaginase: An Ultimate Anti-Neoplastic Enzyme

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Abstract:

The objective of the study described the importance of L-asparaginase and its importance in the field of medicine. Different types of enzymes are produced based on the adaptation to the environment where the living organisms live to tune the metabolic pathways according to their adapted changes. The enzymes present in various organs are produced by many cell types in multicellular organisms. Except ribosomes all other known enzymes are proteinaceous in nature. L-asparaginase is a potential therapeutic agent for acute lymphoblastic leukemia (ALL) and chronic myelogenous leukemia which is approved by FDA & WHO. L-asparaginase catalyzes the deamination of L-asparagine to L-aspartic acid & ammonia. Unlike normal cells, malignant cells require large amount of L-asparagine for protein synthesis and cell division. From this background the present review is an effort to gather the information on the mechanism, sources, molecular details and application of L-asparaginase enzyme.

Info:

Periodical:
International Letters of Natural Sciences (Volume 15)
Pages:
23-35
Citation:
V.S.S.L. P. Talluri et al., "L-Asparaginase: An Ultimate Anti-Neoplastic Enzyme", International Letters of Natural Sciences, Vol. 15, pp. 23-35, 2014
Online since:
May 2014
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Abdel-Fttah Y. R., Olama Z. A., Process Biochemistry 38(1) (2002) 115-122.

Abu Sayem S. M., Alam M. J., Mozammel Hoq Md., Pakisthan Acad. Sci. 43 (2006) 257-262.

Amena S., Vishalakshi N., Prabhakar M., Dayanand A., Lingappa K., Braz. J. Microbiol. 41 (2010) 173-178.

Badr E. I., Foda M. S., Zentralbl Bakteriol Parasetenkd Infektionskr Hyg. 131 (1976) 489-496.

Bascomb S., Banks G. T., Skarstedt M. T., Journal of General Microbiology 91 (1975) 1-16.

Bon E. P., Appl. Biochem. Biotechnol. 63/65 (1997) 203-212.

Boos J., Int J Clin Pharmacol Ther 35 (1997) 96-98.

Borkotaky B., Bezbaruah R. L., Folia Microbiologica 47(5) (2002) 473-476.

Broome J., Nature 171 (1961) 1114.

Bruneau L., Chapman R., Marsolais F., Planta 224 (2006) 668-679.

C. Alves, C. Chaves, M. Souza., Endocrinol Metabol. 51(4) (2007) 635.

C. Liu, J. D. Kawedia, C. Cheng, D. Pei, C. A. Fernandez, X. Cai., Clinical utility and implications of asparaginase antibodies in acute lymphoblastic leukemia. Leukemia., Apr 9, 2012, [Epub ahead of print].

Campbell H., Mashburn L., Boyse E., Old J. L., Biochemistry 6 (1967) 721-730.

Cantor J. R., Stone E. M., Chantranupong L., Georgiou G., Biochemistry 48(46) (2009) 11026-11031.

Cedar H., Schwartz J., Journal of Bacteriology 96(6) (1968) 2043-(2048).

Coral G., Arikan B., Unaldi M. N., Guvenmez H., Annals of microbiology 53 (2003) 491-498.

Curran M. P., Daniel R. M., Guy R. G., Morgan H. W., Arch. Biochem. Biophys. 241 (1985) 571-576.

D. Chiewchengchol, S. Wanankul, N. Noppakun, Pediatric Dermatology 26(1) (2009) 47.

Drainas D., Drainas C., Eur. J. Biochem. 151 (1985) 591-593.

E. Albanese, K. Kafkewitz, Applied and Environmental Microbiology 36(1) (1978) 2530.

Foda M. S., Zedan and Hashem, Acta. Microbiol. Pol. 29 (1980) 343-352.

Friedman M., A review. J. Agric. Food Chem. 51 (2003) 4504-4526.

Goody H. E., Ellem K. A., Biochim Biophys Acta 383 (1975) 30-39.

Gulati R., Saxena R. K., Gupta R., Letters Applied Microbiology 24 (1997) 23-26.

Gunasekaran S., McDonald L., Manavathu M., Manavathu E., Gunasekaran M., Biomedical Letters 52(207) (1995) 197-201.

H. Cohen, B. Bielorai, D. Harats, A. Toren, O. P. Hamiel, Pediatric Blood and Cancer 54(5) (2010) 703.

Handschumacher R. E., Methods Enzymol. Vol. 46 (1977) 432-435.

Hendriksen H. V., Kornbrust B. A., Ostergaard P. R., Stringer M. A., J. Agric. Food Chem. 57 (2009) 4168-4176.

Hosamani R., Kalival B. B., International Journal of Drug Discovery 3(2) (2011) 8899. L. Andrulis, M. T. Barrett, Molecular and Cellular Biology 9(7) (1989) 2922-2927.

Kidd J. G., J. Exp. Med. Vol. 98 (1953) 565-581.

Kil J. O., Kim G. N., Park I., Biotechnol. Biochem. Vol. 59 (1995) 749-750.

Kiriyama Y., Kubota M., Takimoto T., Kitoh T., Tanizawa A., Akiyama Y., Mikawa H., Leukemia 3 (1989) 294-297.

Krishna Suresh Babu Naidu., Lakshmi Devi K., African Journal of Biotechnology 8 (2005) 724-726.

Kukurová K., Morales F. J., Bednáriková A., Ciesarová Z., Mol. Nutr. Food Res. 53 (2009) 1532-1539.

M. H. Kang, Y. H. Kang, B. Szymanska, U. W. Kalak, M. A. Sheard, T. M. Harned, Blood Journal 110(6) (2007) (2057).

Maladkar N. K., Singh V. K., Naik S. R., Hindustan Antibiotic Bull. Vol. 35 (1993) 7786.

Manna S., Sinha A., Sadhukhan R., Chakrabarty S. L., Curr. Microbiol. 30 (1995) 291298.

Mardashev S. R., Nikoaev A. Y., Sokolov N. N., Kozlov E. A., Kutsman M. E., Bokhimiya 40(5) (1975) 984-989.

Mashburn L., Wriston J., Arch Biochem Biophys. 105 (1964) 450.

Mesas J. M., Gil J. A., Martin J. F., J. Gen. Micro Biol. 136 (1990) 515-519.

Michalska K., Bujacz G., Jaskolski, M., J. Mol. Biol. 360 (2006) 105-116.

Michel D., Stefan S., Alina F., Xavier R., Brigitte N., Patrick L., Yves B., Alain R., Anne-Marie M., Etienne V., Jacques O., Noel P., Blood 99 (2002) 2734-2739.

Mickucki J., Szarapinska K. J., Krzeminski Z., Zentralbl. Bakteriol. Parasetenkd. Infektionskr. Hyg. 132(2) (1997) 135-142. (1997).

Mishra A., Appl. Biochem. Biotechnol. Vol. 135 (2006) 33-42.

Mohapatra B. R., Bajpuji M., Banerjee U. C., Cytobios. 92 (1997) 165-173.

Moola Z. B., Biochem. J. 302 (1994) 921-927.

Mostafa S. A., Bacteriol (Naturiviss). 134 (1979) 343-351.

Mostafa S. A., Ali O. A., Zbl. Microbiol. 5 (1983) 397-404.

Mukherjee J., Appl. Microbiol. Biotechnol. 53(2) (200) 180-184.

Nawaz M. S., Zhang D., Khan A. A., Cerniglia C. E., Applied Microbiology and Biotechnology 50(5) (1998) 568-572.

Nefelova M. V., Ross. Prikl. Biokhim Mikrobiol. 14 (1978) 510-514.

Netrval J., Folia Microbiologica 22(2) (1997) 106-116.

Nibha Gupta, SaritaJayanti Dash, Uday Chand Basak, As. Pac J. Mol. Bio. Biotechnol 17(1) (2009) 27-30.

Oza V. P., Trivedi S. D., Parmar, P. P., Subramanian R. B., J Integr Plant Biol. Vol. 51 (2009) 201-206.

Pritsa A. A., Kyriakidis D. A., Mol. Cell. Biochem. 216 (2001) 93-101.

R. Jain, K. U. Zaidi, Y. Verma, P. Saxena., People's Journal of Scientific Research. 5(1) (2012).

Raha S. K., Roy S. K., Dey S. K., Chakrabarty S. L., Biochem. Int. Vol. 21 (1990) 9871000.

Ramakrishnan M. S., Joseph R., Canadian Journal of Microbiology 42(4) (1996) 316325.

Reddy V. K., Reddy S. M., Indian J Microbiol. 30 (1990) 81-83.

Rowly B., Wriston J. C., Biochem Biophys Res Commun. 28 (1967) 160-171.

Rozalska M., Mikucki J., Acta Microbiologica Polonica 41(3-4) (1992) 145-150.

Sahu M. K., Poorani E., Sivakumar K., Thangaradjou T., Kannan L., J. Environ. Biol. 28 (2007) 645-650.

Sanches M., Barbosa J. A. R. G., de Oliveira R. T., Abrahão Neto, J. A., Polikarpov I., Acta Cryst. D59 (2003) 416-422.

Stark R. M., Sulemain M. S., Hsant I. J., Greenman J., Millari M. R., J Med Microbiol. 46 (1997) 793-800.

Stepnyan K. R., Davtyan M. A., Biologicheskii Zhurnal Armenii 41 (1988) 599-603.

Tiul' Panova E. S., Microbiologika 41 (1972) 423-429.

Tiwari N., Dua R. D., Indian J. Biochem Biophys. 33 (1996) 371-376.

Trianfolliou D. J., Georgatsos J. G., Kryiankidis D. A., Mol and cell biochem 81(1) (1988) 43-51.

Tsirka S. A., Kyriakidis D. A., Molecular and Cellular Biochemistry 95(1) (1990) 7788.

Ueno T., Ohtawa K., Mitsui K., Kodera Y., Hiroto M., Matsushima A., Inada Y., Nishimura H., Leukemia 11 (1997) 1858-1861.

Usama F. Ali, Research Journal of Agriculture and Biological Sciences 4 (2008) 886891.

Verma N., Kumar K., Kaur G., Anand S., Crit. Rev. Biotechnol. 27 (2007) 45-62. ( Received 28 April 2014; accepted 05 May 2014 ).

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