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Synthesis and Antifungal Evaluation of Quaternary Ammonium Salts Derivatives of Dialkylaminoethyl Methacrylate Bearing 1,3,4-Oxadiazoles Moieties

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Abstract:

Starting from lauric acid two novel quaternary ammonium salts containing 1,3,4-Oxadiazoles nucleus derivative from N,N-Diethylaminoethyl Methacrylate (DEAEMA) and N,N-Dimethylaminoethyl Methacrylate (DMAEMA) was successfully synthesized and characterized by IR, 1H and 13C NMR, All the synthesized compounds were evaluated for their preliminary in vitro antifungal activity against three fungal strains such as Fusarium oxysporum, Fusarium commune and Fusarium rodelens. The synthesized compounds showed promising antifungal potential against the phytopathogenic test fungi.

Info:

Periodical:
International Letters of Chemistry, Physics and Astronomy (Volume 67)
Pages:
36-41
DOI:
10.18052/www.scipress.com/ILCPA.67.36
Citation:
Z. Ould Kada et al., "Synthesis and Antifungal Evaluation of Quaternary Ammonium Salts Derivatives of Dialkylaminoethyl Methacrylate Bearing 1,3,4-Oxadiazoles Moieties", International Letters of Chemistry, Physics and Astronomy, Vol. 67, pp. 36-41, 2016
Online since:
Jun 2016
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