Subscribe

Subscribe to our Newsletter and get informed about new publication regulary and special discounts for subscribers!

ILCPA > Volume 66 > Synthesis and Characterization of Some Novel...
< Back to Volume

Synthesis and Characterization of Some Novel Coumarin Based 2-Pyridone Heterocycles with their Broad Spectrum Antimicrobial Potency

Full Text PDF

Abstract:

The synthesis of a novel series of 6-((arylidene) amino)-2-oxo-1-((1-(2-oxo-2H-chromen-3-yl) ethylidene) amino)-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitriles 4a-o were synthesized and structures of compounds have been elucidated by IR, 1H NMR, 13C NMR and mass spectral data. Antimicrobial activity was measured against certain strains of bacteria and fungi by serial broth dilution. Evaluation of antimicrobial activity shown that the compounds (4g, 4j, 4k and 4o) were found to be most active against selected bacterial strains and compounds (4d, 4m and 4n) were found to be most active against selected fungal strains.

Info:

Periodical:
International Letters of Chemistry, Physics and Astronomy (Volume 66)
Pages:
1-12
DOI:
10.18052/www.scipress.com/ILCPA.66.1
Citation:
N. C. Desai and T. J. Karkar, "Synthesis and Characterization of Some Novel Coumarin Based 2-Pyridone Heterocycles with their Broad Spectrum Antimicrobial Potency", International Letters of Chemistry, Physics and Astronomy, Vol. 66, pp. 1-12, 2016
Online since:
May 2016
Export:
Distribution: