A series of novel highly substituted pyrimidines bearing furanyl thiazole nucleous have been synthesized. In which reaction of guanidine nitrate with ketene dithioacetals 3c produced substituted pyrimidines 4d which further treated with various aromatic aldehydes to afford title compounds 5(a-t). The chemical structures of the synthesized compounds were elucidated by 1H NMR, 13C NMR, FT-IR, elemental analysis, and mass spectral data.
International Letters of Chemistry, Physics and Astronomy (Volume 60)
H. G. Kathrotiya and Y. T. Naliapara, "Synthesis of Novel Highly Substituted Pyrimidines Bearing Furanyl Thiazole Nucleous", International Letters of Chemistry, Physics and Astronomy, Vol. 60, pp. 47-57, 2015