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International Letters of Chemistry, Physics and Astronomy
Volume 59

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Synthesis, Characterization and Evaluation of Biological Activity of some Substituted(E)-2-Benzylidenehydrazinecarbothio Amides

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Abstract:

A series of substituted (E)-2-benzylidenehydrazinecarbothioamide compounds were synthesized by condensation of thiosemicarbazide with substituted benzaldehydes. The synthesized substituted (E)-2-benzylidenehydrazinecarbothioamide compounds were characterized by their physical constants, UV, IR and NMR spectra. The antimicrobial activities of these synthesized substituted (E)-2-benzylidenehydrazinecarbothioamide compounds have been screened by Bauer-Kirby method using human pathogenic bacteria and fungal species. The antimicrobial activities of all synthesized (E)-2-benzylidenehydrazinecarbothioamide compounds have shown significant activity.

Info:

Periodical:
International Letters of Chemistry, Physics and Astronomy (Volume 59)
Pages:
199-211
DOI:
10.18052/www.scipress.com/ILCPA.59.199
Citation:
R. Vijayakumar et al., "Synthesis, Characterization and Evaluation of Biological Activity of some Substituted(E)-2-Benzylidenehydrazinecarbothio Amides", International Letters of Chemistry, Physics and Astronomy, Vol. 59, pp. 199-211, 2015
Online since:
Sep 2015
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