Paper Titles in Periodical
International Letters of Chemistry, Physics and Astronomy
Volume 59
Subscribe

Subscribe to our Newsletter and get informed about new publication regulary and special discounts for subscribers!

ILCPA > Volume 59 > Synthesis, Hammett Spectral Correlations and...
< Back to Volume

Synthesis, Hammett Spectral Correlations and Antimicrobial Activities of (E)-1-Benzylidene-2-(4-Chlorophenyl)Hydrazines

Download PDF

Abstract:

In the present study, a series of nine number of (E)-1-benzylidene-2-(4-chlorophenyl) hydrazine compounds have been synthesized by condensation reaction of meta and para substituted benzaldehydes with 4-chlorophenylhydrazine using acetic acid catalyst. They are characterized by their physical constants, UV (200-450 nm), Infra-Red (KBr, 4000-400 cm−1) and NMR (1H and 13C) spectral data. The observed UV, IR and NMR spectral data have been correlated with Hammett substituent constants and Swain-Lupton’s F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis the effects of substituents on the spectral data have been discussed. The antimicrobial activities of all the synthesized (E)-1-benzylidene-2-(4-chlorophenyl) hydrazine compounds have been studied using Bauer–Kirby method.

Info:

Periodical:
International Letters of Chemistry, Physics and Astronomy (Volume 59)
Pages:
147-159
DOI:
10.18052/www.scipress.com/ILCPA.59.147
Citation:
M. Rajarajan et al., "Synthesis, Hammett Spectral Correlations and Antimicrobial Activities of (E)-1-Benzylidene-2-(4-Chlorophenyl)Hydrazines", International Letters of Chemistry, Physics and Astronomy, Vol. 59, pp. 147-159, 2015
Online since:
Sep 2015
Export:
Distribution: