Synthesis of N'-(7-Chloroquinolin-4-yl)-6-Methyl-2-Oxo-4-Phenyl-1,2,3,4-Tetrahydropyrimidine-5-Carbohydrazide Derivatives as Potent Antibacterial Agents
Abstract:
Some novel N'-(7-chloroquinolin-4-yl)-6-methyl-2-oxo-4-phenyl-1,2,3,4-tetrahydropyrimidine-5-carbohydrazide derivatives were synthesized via three step reactions by convectional method. The structures of all the compounds have been confirmed by FT-IR, NMR, and MASS and by elemental analysis. We have been evaluated it inhibition capacity for various gram positive and gram negative bacterial strain. All compounds were found to be good to excellent active against all four bacterial strains.
Info:
Periodical:
International Letters of Chemistry, Physics and Astronomy (Volume 56)
Pages:
82-90
Citation:
M. N. Bhoi et al., "Synthesis of N'-(7-Chloroquinolin-4-yl)-6-Methyl-2-Oxo-4-Phenyl-1,2,3,4-Tetrahydropyrimidine-5-Carbohydrazide Derivatives as Potent Antibacterial Agents", International Letters of Chemistry, Physics and Astronomy, Vol. 56, pp. 82-90, 2015
Online since:
July 2015
Keywords:
Distribution:
Open Access
This work is licensed under a
Creative Commons Attribution 4.0 International License
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Cited By:
[1] M. Borad, M. Bhoi, S. Rathwa, M. Vasava, H. Patel, C. Patel, H. Pandya, E. Pithawala, J. Georrge, "Microwave-Assisted ZrSiO2 Catalysed Synthesis, Characterization and Computational Study of Novel Spiro[Indole-Thiazolidines] Derivatives as Anti-tubercular Agents", Interdisciplinary Sciences: Computational Life Sciences, 2016
DOI: https://doi.org/10.1007/s12539-016-0195-2