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International Letters of Chemistry, Physics and Astronomy
Volume 56


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Synthesis, Characterization and Antimicrobial Activity of some New Oxadiazole Derivatives in DMSO and DMF

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A series of oxadiazole derivatives were synthesized and were characterized by IR, 1H NMR and mass spectroscopy. All these synthesized compounds were tested for in vitro antimicrobial against four Gram positive bacteria, four Gram negative bacteria and four fungal strains in DMSO and DMF.


International Letters of Chemistry, Physics and Astronomy (Volume 56)
S. Baluja et al., "Synthesis, Characterization and Antimicrobial Activity of some New Oxadiazole Derivatives in DMSO and DMF", International Letters of Chemistry, Physics and Astronomy, Vol. 56, pp. 104-112, 2015
Online since:
Jul 2015

[1] S. N. Bhardwaj, S. K. Saraf, P. Sharma, P. Kumar, Syntheses, evaluation and characterization of some 1, 3, 4-oxadiazoles as antimicrobial agents, Eur. J. Chem., 6 (2009) 1133-1138.

[2] M. A. A. Omar, Synthesis and antimicrobial activity of new 5-(2- thienyl)-1, 2, 4-triazoles and 5-(2-thienyl)-1, 3, 4-oxadiazoles and related derivatives, Molecules., 15 (2010) 502-514.

DOI: 10.3390/molecules15010502

[3] A. Rathavi, M. Shukla, M. K. Thakor, Design, synthesis and antimicrobial screening of S-triazinyl derivatives containing 1, 3, 4-oxadiazole ring, Archives of Applied Science Research, 6 (2014) 82-89.

[4] A. Kumar, S. Singh, M. Verma, A. K. Saxena, K. Shanker, Potent anti-inflammatory 2-(o-hydroxyphenyl)-5-(p-dimethylaminophenyl)-1, 3, 4-oxadiazoles, Ind. J. Pharm. Sci., 49 (1987) 201-204.

[5] M. M. Burbuliene, V. Jakubkiene, G. Mekuskiene, E. Udrenaite, R. Smicius, P. Vainilavicius, Synthesis and anti-inflammatory activity of derivatives of 5-[(2-disubstitutedamino-6-methylpyrimidin-4-yl)-sulfanylmethyl]-3H-1, 3, 4-oxadiazole-2-thiones, IL Farmaco., 59 (2004).

DOI: 10.1016/j.farmac.2004.05.007

[6] A. H. Samir, A. H. Jawad, Z. M. Malik, Al-Rubaei, In vitro study of the effect of some prepared oxadiazole derivatives on ALP, AST and ALT activities in sera of hepatocellular cancer patients and healthy control, Journal of Al-Nahrain University, 13 (2010).

[7] E. D. Chrysina, M. N. Kosmopoulou, C. Tiraidis, R. Kardakaris, N. Bischler, D. D. Leonidas, Z. Hadady, L. Somsak, T. Docsa, P. Gergely, N. G. Oikonomakos, Kinetic and crystallographic studies on 2-(β-D-glucopyranosyl-5-methyl- 1, 3, 4-oxadiazole, -benzothiazole, and-benzimidazole, inhibitors of muscle glycogen phosphorylase b. Evidence for a new binding site. Protein Sci., 14, (2005).

DOI: 10.2210/pdb1xkx/pdb

[8] P. Patrao, A. M. A. Khader, B. Kalluray, Vinayachandra, Synthesis of new 5-naphthyl substituted 1, 3, 4-oxadiazole derivatives and their antioxidant activity, Der Pharma Chemica, 5 (2013) 24-32.

[9] J. Parekh, P. Inamdhar, R. Nair, S. Baluja, S. Chanda, Synthesis and antibacterial activity of some Schiff bases derived from 4-aminobenzoic acid, J. Serb. Chem. Soc., 70 (2005) 1155-1158.

DOI: 10.2298/jsc0510155p
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