Paper Titles in Periodical
International Letters of Chemistry, Physics and Astronomy
Volume 53
Subscribe

Subscribe to our Newsletter and get informed about new publication regulary and special discounts for subscribers!

ILCPA > Volume 53 > Synthesis and Characterization of Novel...
< Back to Volume

Synthesis and Characterization of Novel N-(Benzo[d]Thiazol-2-yl)-2-(2-(6-Chloroquinolin-4-yl)Hydrazinyl)Acetamide Derivatives Containing Quinoline Linkage as Potent Antibacterial Agents

Download PDF

Abstract:

As part of ongoing studies in developing new antibacterial agent, a novel series of N-(benzo[d]thiazol-2-yl)-2-(2-(6-chloroquinolin-4-yl)hydrazinyl)acetamide derivatives was synthesized by sequencing reaction of 2-aminobenzothiazole with chloroacetylchloride, hydrazine hydrate and 4,7-dichloroquinoline. The novel heterocycles were characterized by elemental analyses and various spectroscopic techniques. The synthesized compounds were tested in-vitro antibacterial activity against two Gram-positive and two Gram-negative bacteria with standard drugs. Microbiological results showed that the synthesized compounds possessed a broad spectrum of antibacterial activity against the tested microorganisms.

Info:

Periodical:
International Letters of Chemistry, Physics and Astronomy (Volume 53)
Pages:
114-121
DOI:
10.18052/www.scipress.com/ILCPA.53.114
Citation:
M. N. Bhoi et al., "Synthesis and Characterization of Novel N-(Benzo[d]Thiazol-2-yl)-2-(2-(6-Chloroquinolin-4-yl)Hydrazinyl)Acetamide Derivatives Containing Quinoline Linkage as Potent Antibacterial Agents", International Letters of Chemistry, Physics and Astronomy, Vol. 53, pp. 114-121, 2015
Online since:
Jul 2015
Export:
Distribution: