The benzothiazole and Schiff base moieties are crucial functionalities due to their wide variety of biological activities and have a wide range of therapeutic properties. Keeping in view the importance of these organic moieties, a new series of 2-Aminobenzothiazole containing novel Schiff bases derivatives were synthesized by sequential reaction. The structures of the synthesized compounds were confirmed by their analytical and spectral data. The synthesized compounds were evaluated for their in vitro antibacterial activity against gram positive and gram negative bacteria. Synthesized compounds showed significant activity against microorganisms, which can be correlated with the privileged heterocyclic structural scaffolds.
International Letters of Chemistry, Physics and Astronomy (Volume 53)
M. N. Bhoi et al., "2-Aminobenzothiazole Containing Novel Schiff Bases Derivatives: Search for New Antibacterial Agents", International Letters of Chemistry, Physics and Astronomy, Vol. 53, pp. 106-113, 2015