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International Letters of Chemistry, Physics and Astronomy
ILCPA Volume 52

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Synthesis and Antimicrobial Activities of Novel Palladium (II) Complexes of Active Schiff’s Base Ligand Derived from 5-Bromo Isatin

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This paper presents the synthesis and antimicrobial studies of Palladium (II) complexes of ThioSemicarbazone Pd (L1H)2Cl2 and Semicarbazone Pd (L2H)2Cl2 derived from 5-Bromo Isatin. All complexes reported here had been characterised by1H NMR and IR spectral studies .the complexes are diamagnetic in nature and showing square planner geometry. The IR spectral data reveals that both the Schiff’s bases behave as bidentate ligands and are co-ordinated to Pd (II) metal through the sulfur and hydrogenic nitrogen atom. All the new synthesized compounds were screened for antibacterial activity against four of the test organisms like Bacillus pumilus, Micrococcus Lutes, E.coli, Salmonella abony.


International Letters of Chemistry, Physics and Astronomy (Volume 52)
A. N. Patange et al., "Synthesis and Antimicrobial Activities of Novel Palladium (II) Complexes of Active Schiff’s Base Ligand Derived from 5-Bromo Isatin", International Letters of Chemistry, Physics and Astronomy, Vol. 52, pp. 22-27, 2015
Online since:
June 2015

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[1] A. Ali, S. Teoh, N. Eltayeb, M. Khadeer Ahamed, A. Abdul Majid, A. Almutaleb, "Synthesis, structure and in vitro anticancer, DNA binding and cleavage activity of palladium (II) complexes based on isatin thiosemicarbazone derivatives", Applied Organometallic Chemistry, Vol. 31, p. e3813, 2017


[2] G. Munikumari, R. Konakanchi, V. Nishtala, G. Ramesh, L. Kotha, K. Chandrasekhar, C. Ramachandraiah, "Palladium(II) complexes of 5-substituted isatin thiosemicarbazones: Synthesis, spectroscopic characterization, biological evaluation and in silico docking studies", Synthetic Communications, Vol. 49, p. 146, 2019


[3] T. Yusuf, E. Akintemi, S. Olagboye, G. Tolufashe, "Investigating the biological actions of some Schiff bases using density functional theory study", Physical Sciences Reviews, Vol. 0, 2021