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International Letters of Chemistry, Physics and Astronomy
ILCPA Volume 49

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Synthesis and Electrochemical Properties of N-(Ferrocenylmethyl)Aminobenzonitrile and N-(Ferrocenylmethyl)Nitroaniline Derivatives

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Seven novel ferrocene derivatives containing (methylamino)benzonitrile and N-methylnitroaniline groups (3a-3f and 4) have been synthesized by conventional methods and characterized by FT-IR, NMR and cyclic voltammetry. The electrochemical behavior of these compounds (3a-3f) has been studied by cyclic voltammetry measurements at a platinum electrode in acetonitrile/0.1 M TBAP. The ferrocenyl group in all compounds showed similar reversible one-electron redox process, suggesting that the ferrocene moieties are equivalent and that there are no interactions among them. The formal potential, , is shifted to the more positive potential, indicating that the (methylamino)benzonitrile and N-methylnitroaniline introduced to ferrocene moiety exercise an electron-withdrawing effect.


International Letters of Chemistry, Physics and Astronomy (Volume 49)
C. Boubekri et al., "Synthesis and Electrochemical Properties of N-(Ferrocenylmethyl)Aminobenzonitrile and N-(Ferrocenylmethyl)Nitroaniline Derivatives", International Letters of Chemistry, Physics and Astronomy, Vol. 49, pp. 27-34, 2015
Online since:
April 2015

I. U. Khand, T. Lanez, P. L. Pauson, J. Chem. Soc. Perkin Trans. 1 (1989) 2075-(2078).

Z. Szarka, Á. Kuik, R. Skoda-Földes, L. Kollár, J. Organomet. Chem. 689 (2004) 2770-2775.

R.D.A. Hudson, J. Organomet. Chem. 637 (2001) 47-69.

M. Uno, P.H. Dixneuf, Angew. Chem. Int. Ed. Engl. 37(1998) 1714-1717.

J. Isaad, F. Salaun , Sensors and Actuators B 157 (2011) 26-33.

J. C. Torres, R. A. Pilli, M. D. Vargas, F. A. Violante, S. J. Garden, A. C. Pinto, Tetrahedron 58 (2002) 4487-4492.

N. Chavain, E. Davioud-Charvet, X. Trivelli, L. Mbeki, M. R. R. Brun, C. Biot, Bioorg. Med. Chem. 17 (2009) 8048-8059.

D. A. Ralambomanana , D. Razafimahefa-Ramilison , A. Clément Rakotohova , J. Maugein, L. Pélinski, Bioorg. Med. Chem. 16 (2008) 9546-9553.

M. Suzan, M. I. Batterjee, M. Marzouk, M. E. Aazab, A. El-Hashash, Appl. Organomet. Chem. 17 (2003) 291-297.

S. Ezzaher, J. F. Capon, N. Dumontet, F. Gloaguen, F. Y. Pétillon, P. Schollhammer, J. Talarmin, J. Electroanal. Chem. 626 (2009) 161-170.

J. M. Lloris, R. Martínez-Máňez, J. Soto, T. Pardo, J. Organomet. Chem. 637 (2001) 151158.

T. Zaiz, T. Lanez. J. Fundam. Appl. Sci. 4(2), 2012, 182-191.

P. N. Kelly, A. Prêtre , S. Devoy , I. O'Rielly, R. Devery, A. Goel, J. F. Gallagher, A. J. Lough, P. T.M. Kenny, J. Organomet. Chem. 692 (2007) 1327-1331.

M. Zora, Ö. Velioğlu, J. Organomet. Chem, 693 (2008) 2159-2162.

B. Shaabani, Z. Shaghaghi, Tetrahedron, 66 (2010) 3259-3264.

C. Imrie, V. O. Nyamori, T. I. A Gerber, J. Organomet. Chem, 689 (2004)1617-1622.

L. V. Popova,V. N. Babin,Y. A. Belousov,Y. S. Nekrasov, A. E. Snegireva, N. P. Borodina, G. M. Shaposhnikova, O. B. Bychenko, P. M. Raevskii, N. B. Morozova, A. I. Iiyina, K. G. Shitkov, Appl. Organomet. Chem. 7(2) (1993)85-94.

Ž. Petrovski, M. R.P. Norton de Matos, S. S. Braga, C. C.L. Pereira, M. L. Matos, I. S. Gonçalves, M. Pillinger, P. M. Alves, C. C. Romão, J. Organomet. Chem. 693 (2008) 675684.

J. M. Osgerby, P. L. Pauson, J. Chem. Soc. 642 (1958) 656-660.

D. D. Perrin, W. L. F. Armarego, Purification of Laboratory Chemicals, Pergamon Press: New York, (1988). ( Received 07 March 2015; accepted 22 March 2015 ).

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[1] T. Lanez, E. Lanez, "A Molecular Docking Study of N-Ferrocenylmethylnitroanilines as Potential Anticancer Drugs", International Journal of Pharmacology, Phytochemistry and Ethnomedicine, Vol. 2, p. 5, 2016


[2] A. Khennoufa, L. Bechki, T. Lanez, E. Lanez, N. Zegheb, "Spectrophotometric, voltammetric and molecular docking studies of binding interaction of N-ferrocenylmethylnitroanilines with bovine serum albumin", Journal of Molecular Structure, Vol. 1224, p. 129052, 2021