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International Letters of Chemistry, Physics and Astronomy
ILCPA Volume 49
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Synthesis, Spectral Studies, Antibacterial and Antifungal Activity of 2"-Methoxy-4"-[2 -(4'-Chlorophenyl)-6-Methyl Imidazo[1, 2-a]Pyridin-3-yl]-6"-Aryl Nicotinonitrile
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Synthesis, Spectral Studies, Antibacterial and Antifungal Activity of 2"-Methoxy-4"-[2 -(4'-Chlorophenyl)-6-Methyl Imidazo[1, 2-a]Pyridin-3-yl]-6"-Aryl Nicotinonitrile

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Abstract:

Pyridine nucleus plays an important role in medicine, agriculture and industrial chemistry. With a view of biological activities and variety of industrial applications, some new 2" – methoxy - 4" - [2 - ( 4' -chlorophenyl)-6-methyl imidazo [1, 2-a] pyridin-3-yl]-6"-aryl nicotinonitrile( 4a-4l ) has been synthesized. The products have been assayed for their biological activity against Gram +ve, Gram –ve bacteria and fungi. Some of the products showed moderate activity in concentration 50µg/ml. The structures of the products have been elucidated by IR, 1H-NMR, Mass spectral data, elemental analysis and thin layer chromatography.

Info:

Periodical:
International Letters of Chemistry, Physics and Astronomy (Volume 49)
Pages:
155-160
DOI:
https://doi.org/10.18052/www.scipress.com/ILCPA.49.155
Citation:
V.V. Bhuva et al., "Synthesis, Spectral Studies, Antibacterial and Antifungal Activity of 2"-Methoxy-4"-[2 -(4'-Chlorophenyl)-6-Methyl Imidazo[1, 2-a]Pyridin-3-yl]-6"-Aryl Nicotinonitrile", International Letters of Chemistry, Physics and Astronomy, Vol. 49, pp. 155-160, 2015
Online since:
April 2015
Authors:
V.V. Bhuva, V.N. Bhadani, H.D. Purohit, Dipak M. Purohit
Keywords:
2-Methoxy-3-Cyanopyridine, Antibacterial Activity, Antifungal Activity
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Distribution:
Open Access

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