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ILCPA > Volume 42 > Bio-Potent (5-Chloro-2-Thienyl)-3-(Substituted...
Bio-Potent (5-Chloro-2-Thienyl)-3-(Substituted Phenyl) Bicyclo[2.2.1]Heptane-2-yl Methanone Derivatives
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Bio-Potent (5-Chloro-2-Thienyl)-3-(Substituted Phenyl) Bicyclo[2.2.1]Heptane-2-yl Methanone Derivatives

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Abstract:

A series of (5-chloro-2-thienyl)(3-(substituted phenyl) bicyclo [2.2.1] hept-5-en-2-yl) methanones have been synthesized by fly-ash catalyzed [4+2] cycloaddition Diels-Alder reaction of cyclopentadiene and 5-chloro-2-thienyl chalcones under cooling conditions. The yields of the methanones are more than 60%. The synthesized (5-chloro-2-thienyl)(3-(substituted phenyl) bicyclo [2.2.1] hept-5-en-2-yl) methanones are characterized by their physical constants and spectral data. The antimicrobial, antioxidant and insect antifeedant activities of synthesized methanones have been studied using their respective bacterial, fungal strains, DPPH radical scavenging activity and Dethler’s leaf-discs bioassay method.

Info:

Periodical:
International Letters of Chemistry, Physics and Astronomy (Volume 42)
Pages:
1-12
DOI:
https://doi.org/10.18052/www.scipress.com/ILCPA.42.1
Citation:
G. Thirunarayanan "Bio-Potent (5-Chloro-2-Thienyl)-3-(Substituted Phenyl) Bicyclo[2.2.1]Heptane-2-yl Methanone Derivatives", International Letters of Chemistry, Physics and Astronomy, Vol. 42, pp. 1-12, 2015
Online since:
December 2014
Authors:
Ganesamoorthy Thirunarayanan
Keywords:
5-Chloro-2-Thienyl Chalcones, Antimicrobial Activities, Antioxidant Activity, Cyclopentadiene, Diels-Alder Reaction, Insect Antifeedant Activity
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Distribution:
Open Access

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This work is licensed under a
Creative Commons Attribution 4.0 International License

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