Synthesis and Characterization of Substituted Bisbenzoxazine as Potent Antimicrobial Agent

Lalcheta, Kishor R.; Dhaduk, Bhvin B.; Mendapara, Jaymin P.

doi:10.18052/www.scipress.com/ILCPA.40.73

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Synthesis and Characterization of Substituted Bisbenzoxazine as Potent Antimicrobial Agent

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Abstract:

Bisbenoxazines derivatives were synthesized by refluxing substituted bisphenol-C, substituted aniline and formaldehyde in presence of 1,4-dioxane with good yields. All the synthesized compounds were characterized by mass, NMR and IR and also evaluated for antimicrobial activity against four different bacterial and two fungal strains. The compounds 1c, 1h, 1j and 1l has found comparatively good active against all the bacterial strains.

Info:

Periodical:

International Letters of Chemistry, Physics and Astronomy (Volume 40)

Pages:

73-80

DOI:

https://doi.org/10.18052/www.scipress.com/ILCPA.40.73

Citation:

K. R. Lalcheta et al., "Synthesis and Characterization of Substituted Bisbenzoxazine as Potent Antimicrobial Agent", International Letters of Chemistry, Physics and Astronomy, Vol. 40, pp. 73-80, 2015

Online since:

October 2014

Authors:

Kishor R. Lalcheta, Bhvin B. Dhaduk, Jaymin P. Mendapara

Keywords:

Benzoxazines, Microbial Activity, Spectral Techniques, Synthesis

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Creative Commons Attribution 4.0 International License

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[1] D. Zinad, A. Mahal, R. Mohapatra, A. Sarangi, M. Pratama, "Medicinal chemistry of oxazines as promising agents in drug discovery", Chemical Biology & Drug Design, 2019

DOI: https://doi.org/10.1111/cbdd.13633