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International Letters of Chemistry, Physics and Astronomy
Volume 39

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Synthesis and Characterization of some Benzylidinehydrazinyl Derivatives of Newer Pyrimidine-5-Carbonitrile Moiety

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Abstract:

Condensation of 2-hydrazinyl-1,6-dihydro-1-methyl-6-oxo-4-isobutylpyrimidine-5-carbonitrile (3) with different aromatic aldehyde gave the corresponding 2-(Benzylidinehydrazinyl)-1,6-dihydro-6-oxo-4-isobutylpyrimidine-5-carbonitrile (4). The reaction between 1,6-dihydro-1-methyl-2-(methylthio)-6-oxo-4-isobutylpyrimidine-5-carbonitrile (2) with hydrazine hydrate furnished (3). The condensation of 1,2,3,4-tetrahydro-4-oxo-6-isobutyl-2-thioxopyrimidine-5-carbonitrile (1) with methyl iodide yielded 2. Finally the products were characterized by 1H NMR, Mass and IR Spectra.

Info:

Periodical:
International Letters of Chemistry, Physics and Astronomy (Volume 39)
Pages:
28-34
DOI:
10.18052/www.scipress.com/ILCPA.39.28
Citation:
H. Dhaval et al., "Synthesis and Characterization of some Benzylidinehydrazinyl Derivatives of Newer Pyrimidine-5-Carbonitrile Moiety", International Letters of Chemistry, Physics and Astronomy, Vol. 39, pp. 28-34, 2014
Online since:
Oct 2014
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References:

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