Pharmacological and Insect Antifeedant Activities of some 3-(2,4-Dichloro-5-Fluorophenyl)-5-(Substituted Phenyl)-4,5-Dihydro-1H-Pyrazole-1-Carbothioamides

Thirunarayanan, Ganesamoorthy

doi:10.18052/www.scipress.com/ILCPA.37.47

ILCPA > ILCPA Volume 37 > Pharmacological and Insect Antifeedant Activities...

< Back to Volume

Pharmacological and Insect Antifeedant Activities of some 3-(2,4-Dichloro-5-Fluorophenyl)-5-(Substituted Phenyl)-4,5-Dihydro-1H-Pyrazole-1-Carbothioamides

Full Text PDF

Abstract:

A series containing twelve titled compounds were synthesized by solvent-free method and their purities were examined by literature procedure. These compounds were subjected to study the pharmacological effects such as antibacterial, antifungal and antioxidant activities and the insect antifeedant activities using Bauer-Kirby disc diffusion method with their bacterial and fungal strains, DPPH radical scavenging and leaf disc bio-assay method with 4th instar larvae Achoea janata L.

Info:

Periodical:

International Letters of Chemistry, Physics and Astronomy (Volume 37)

Pages:

47-56

DOI:

https://doi.org/10.18052/www.scipress.com/ILCPA.37.47

Citation:

G. Thirunarayanan, "Pharmacological and Insect Antifeedant Activities of some 3-(2,4-Dichloro-5-Fluorophenyl)-5-(Substituted Phenyl)-4,5-Dihydro-1H-Pyrazole-1-Carbothioamides", International Letters of Chemistry, Physics and Astronomy, Vol. 37, pp. 47-56, 2014

Online since:

August 2014

Authors:

Ganesamoorthy Thirunarayanan

Keywords:

Antibacterial Activity, Antifungal Activity, Antioxidant Activity, Halo Aryl 4,5-Dihydro-1H-Pyrazole-1-Carbothioamides, Insect Antifeedant Activities

Export:

RIS, BibTeX, Text

Distribution:

Open Access

This work is licensed under a
Creative Commons Attribution 4.0 International License

References:

[1] S. P. Sakthinathan, G. Vanangamudi, G. Thirunarayanan, Spectrochim. Acta. 95A (2012) 693-700.

[2] S. Sasikala, K. Thirumurthy, P. Mayavel, G. Thirunarayanan, Org. Med. Chem. Lett. (2012) doi: 10. 1186/2191-2858-2-20.

[3] P. Descacq, A. Nuhrich, M. Capdepuy, G. Devaux, Eur. J. Med. Chem. 25 (1990) 285-290.

[4] S. Cihat, T. Ayla, S. Selma, Y. Nuran, J. Indian Chem. Soc. 67 (1990) 571-573.

[5] N. M. Abunada, H. M. Hassaneen, N. G. Kandile, O. A. Miqdad, Molecules. 13 (2008) 1011-1024.

[6] R. Mishra, A. Siddiqui, A. Rahman, Shaharyar, Chem. Sci. J. (2010) 783-790.

[7] S. Kumar, S. Bawa S, S. Drabu, R. Kumar, H. Gupta, Recent Patents on Anti-Infective Drug Discovery 4 (2009) 154-163.

DOI: https://doi.org/10.2174/157489109789318569

[8] S. A. F. Rostom, Bioorg. Med. Chem. 14 (2006) 6475-6485.

[9] A. Solankee, S. Solankee, G. Patel, Rasayan J. Chem. 3 (2008) 581-585.

[10] S. Sahu, M. Banerjee, A. Samantra, C. Behera, Tropical J. Pharm. Res. 7 (2008) 961-968.

[11] A. Mathew, T. L. Mary Sheeja, T. Arun Kumar,K. Radha, Hygeia. J. D. Med. 3 (2011) 48-56.

[12] N. Mishra, D. Sasmal, Bioorg. Med. Chem. Lett. 21 (2011) 1969-(1973).

[13] G. Thirunarayanan, V. Renuka, K. G. Sekar, K. Lakshmanan, K. Anbarasu, International Letters of Chemistry, Physics and Astronomy 4 (2014) 66-81.

[14] G. Thirunarayanan, Q-Science Connect, (2014) DOI: http: /dx. doi. org/ 10. 5339/ connect. 2014. 18.

[15] P. C. Lv, H. Q. Li, J. Sun, Y. Zhou, H. L. Zhu, Bioorg. Med. Chem. 18 (2010) 4606-4614.

[16] V. S. Patil, S. J. Wadher, N. A. Karande, P. G. Yeole, Int. J. Univ. Pharm. Life. Sci. 1 (2011) 16-22.

[17] Z. Özdemir, H. B. Kandilci, B. Gümüsef, Ü. Çalis, A. A. Bilgin, Eur. J. Med. Chem. 42 (2007) 373-379.

[18] J. T. Li, Y. Yin, L. Li, M. X. Sun, Ultrasonics Sonochem. 17 (2010) 11-13.

[19] R. Gupta, N. Gupta, A. Jain, Indian J. Chem. 49B (2010) 351-355.

[20] L. Pizzuti, L. A. Piovesan, A. F. C. Flores, F. H. Quina and C. M. P. Pereira, Ultrasonics Sonochem 16 (2009) 728-731.

[21] R. Chawla, U. Sahoo, A. Arora, P. C. Sharma, V. Radhakrishnan, Acta. Poloniae. Pharm. Drug Res. 67 (2010) 55-61.

[22] V. M. Patil, K. R. Desai, Arkivoc. 1 (2004) 123-129.

[23] K. G. Sekar, G. Thirunarayanan, Int. J. Sci. Res. Know. 1(8) (2013) 299-307.

[24] G. Thirunarayanan, K, G. Sekar, Org. Chem.: An Indian J. 10(1) (2014) 43-52.

[25] G. Thirunarayanan, K. G. Sekar, International Letters of Chemistry, Physics and Astronomy 10(1) (2013)18-34.

[26] G. Thirunarayanan, K. Sekar, Q-Science Connect. (2013). DOI http: /dx. doi. org/10. 5339, 2013. 18.

[27] G. Thirunarayananm, K. Sekar, Org. Chem: An Indian J. 9(12) (2013) 483-492.

[28] K. Ranganathan, R. Suresh, G. Vanangamudi, K. Thirumurthy, P. Mayavel, G. Thirunarayanan, Bull. Chem. Soc. Ethiop. 28(2) (2014) 271-288.

[29] G. Thirunarayanan, International Letters of Chemistry, Physics and Astronomy 5 (2014) 89-98.

[30] G. Thirunarayanan, P. Mayavel, K. Thirumurthy, S. Dineshkumar, R. Sasikala, P. Nisha, A. Nithyaranjani, European Chem. Bull. 2(9) (2013) 598-605.

[31] G. Thirunarayanan, K. Ravi, International Letters of Chemistry, Physics and Astronomy 14 (2013) 44-57.

[32] G. Thirunarayanan, K. G. Sekar, J. Saudi Chem. Soc. (2013). DOI: 10. 1016/j. jscs. 2013. 12. 002.

[33] A. W. Bauer, W. M. M. Kirby, J.C. Sherris, M. Truck, Am. J. Clin. Pathol. 45 (1966) 493-498.

[34] G. Vanangamudi, M. Subramanian, G. Thirunarayanan, Arabian J. Chem. (2013) DOI: 10. 1016/j. arabjc. 2013. 03. 006.

[35] K. Ranganathan, R. Suresh, D. Kamalakkannan, R. Arulkumaran, R. Sundararajan, S. P. Sakthinathan, S. Vijayakumar, G. Vanangamudi, K. Thirumurthy, P. Mayavel, G. Thirunarayanan, International Letters of Chemistry, Physics and Astronomy 4 (2012).

DOI: https://doi.org/10.18052/www.scipress.com/ilcpa.4.66

[36] G. Thirunarayanan, K. G. Sekar, Int. J. Chem. 2(4) (2013) 513-526.

[37] V. G. Dethler's, Chemical Insect Attractants and Repellents, Blackistan, Philadelphia. 1947; p.210. ( Received 16 July 2014; accepted 25 July 2014 ).

Show More Hide

Cited By:

This article has no citations.