The Cancer Cell Plasma Membrane Potentials as Energetic Equivalents to Astrophysical Properties

Persinger, Michael A.; Lafrenie, Robert M.

doi:10.18052/www.scipress.com/ILCPA.36.67

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The Cancer Cell Plasma Membrane Potentials as Energetic Equivalents to Astrophysical Properties

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Abstract:

The primary physical and chemical parameters that define the hypopolarized plasma cell membrane of malignant (cancer) cells compared to non-malignant cells reflect universal characteristics. The median value for the resting membrane potential is the constant for the Nernst equation without reference to discrepancies in ion concentrations and is identical to Boltzmann energies at 37 °C. The threshold energy defining space-time converges with access to entropic processes that are reflected in the morphology of cancer cells and tumors. Slowing of growth in cancer cell lines but not normal cells following exposure to weak (~1 to 10 μT) patterned magnetic fields occurs when the energy induced within the cell corresponds to the energy equivalent of the hypopolarized membrane potential. The optimal temporal parameters for the efficacy of these fields can be derived from Hubble‟s parameter and the transform function for “noise” or “random” patterns within the system. Quantitative solutions and experimental data indicate that the cancer cell may be dominated by entropic process that can be attenuated or blocked by temporally-structured applied magnetic fields whose intensity matches the increment of energy associated with this threshold.

Info:

Periodical:

International Letters of Chemistry, Physics and Astronomy (Volume 36)

Pages:

67-77

DOI:

https://doi.org/10.18052/www.scipress.com/ILCPA.36.67

Citation:

M. A. Persinger and R. M. Lafrenie, "The Cancer Cell Plasma Membrane Potentials as Energetic Equivalents to Astrophysical Properties", International Letters of Chemistry, Physics and Astronomy, Vol. 36, pp. 67-77, 2014

Online since:

July 2014

Authors:

Michael A. Persinger, Robert M. Lafrenie

Keywords:

Cancer Cell, Entropy, Hubble’s Parameter, kT Boundary, Magnetic Energy, Noise Band

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Open Access

This work is licensed under a
Creative Commons Attribution 4.0 International License

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Cited By:

[1] M. Persinger, B. Dotta, D. Vares, S. Koren, "Shifts in Photon Spectral Power Densities within Schumann (7.7 to 7.8 Hz) Values in Microtubules during Complex Magnetic Field Exposures May Reflect an Information Interface with Universal Energies", Open Journal of Biophysics, Vol. 05, p. 84, 2015

DOI: https://doi.org/10.4236/ojbiphy.2015.53008

[2] C. Buckner, A. Buckner, S. Koren, M. Persinger, R. Lafrenie, "The effects of electromagnetic fields on B16-BL6 cells are dependent on their spatial and temporal character", Bioelectromagnetics, Vol. 38, p. 165, 2017

DOI: https://doi.org/10.1002/bem.22031

[3] L. Ochoo, C. Migwi, J. Okumu, "Important parameters for optimized metal nanoparticles-aided electromagnetic field (EMF) effect on cancer", Cancer Nanotechnology, Vol. 9, 2018

DOI: https://doi.org/10.1186/s12645-018-0038-4

[4] X. Li, F. Yang, B. Rubinsky, "A Theoretical Study on the Biophysical Mechanisms by Which Tumor Treating Fields Affect Tumor Cells During Mitosis", IEEE Transactions on Biomedical Engineering, Vol. 67, p. 2594, 2020

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[5] X. Li, F. Yang, B. Rubinsky, "A Correlation Between Electric Fields That Target the Cell Membrane Potential and Dividing HeLa Cancer Cell Growth Inhibition", IEEE Transactions on Biomedical Engineering, Vol. 68, p. 1951, 2021

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[6] E. Jenkins, A. Finch, M. Gerigk, I. Triantis, C. Watts, G. Malliaras, "Electrotherapies for Glioblastoma", Advanced Science, p. 2100978, 2021

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