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Synthesis and Characterization of some New Schiff Bases of 2-Oxonaphtho[2,1-b][1,4]Oxazine

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Abstract:

The literature review reveal that [1,4]-oxazine derivatives represent one of the most active classes of compounds possessing wide spectrum of biodynamic activities and use as potent therapeutic agents. In the present work, a series of Schiff base of 2-(2,3-dihydro-2-oxonaphtho[2,1-b][1,4]oxazin-1-yl)acetohydrazide, 5a-5j has been synthesized using 1-aminonaphthalen-2-ol. Various aromatic aldehyde were react with carbohydrazide 4 in the presence of acid to produce the 2-oxonaphtho[2,1-b][1,4]oxazin Schiff base derivatives with good yields. All synthesized compounds were characterized by IR, NMR and Mass spectrometry analysis.

Info:

Periodical:
International Letters of Chemistry, Physics and Astronomy (Volume 31)
Pages:
26-30
Citation:
P. Chovatiya et al., "Synthesis and Characterization of some New Schiff Bases of 2-Oxonaphtho[2,1-b][1,4]Oxazine", International Letters of Chemistry, Physics and Astronomy, Vol. 31, pp. 26-30, 2014
Online since:
March 2014
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