Some new dihydropyrano[c]chromenes derivatives are synthesized from 4-hydroxycoumarin. The structure of newly synthesized compounds was confirmed by mass, 1H NMR and IR spectroscopy. Further, antimicrobial screening of these synthesized compounds was done against some bacterial (Gram positive as well as Gram negative) and fungal strains in N,N-dimethylformamide. It is observed that some of synthesized compounds exhibited significant antibacterial activity against Gram positive bacterial strains. The selected fungal strains were most resistant for the studied compounds as none of the synthesized compounds showed activity against any of the fungal strain studied. The best antibacterial activity was shown by ABR-10.
International Letters of Chemistry, Physics and Astronomy (Volume 31)
A. A. Bhalu et al., "Synthesis, Characterization and Antimicrobial Activity of some New Dihydropyrano[c] Chromenes", International Letters of Chemistry, Physics and Astronomy, Vol. 31, pp. 1-6, 2014