Paper Titles in Periodical
International Letters of Chemistry, Physics and Astronomy
Volume 30
Subscribe

Subscribe to our Newsletter and get informed about new publication regulary and special discounts for subscribers!

ILCPA > Volume 30 > Convenient Synthesis of the 2,5-di-Substituted...
< Back to Volume

Convenient Synthesis of the 2,5-di-Substituted 1,3,4-Oxadiazole Derivatives under Microwave

Download PDF

Abstract:

We have reported some novel 1,3,4-oxadiazole synthesized by conventional method as well as microwave assisted method. The reaction of different substituted cinnamic acid 2a-o with 2-(4-chlorophenyl) acetohydrazide by using phosphoric anhydride as catalyst, yielded a series of 2,5-di-substituted 1,3,4-oxadiazole 6a-o. The structures of all synthesized compounds are well characterized by Mass, FT-IR, 1H NMR, 13C NMR and elemental analysis. After obtaining experimental data regarding the yield and the time taken for the synthesis by both the methods, conventional and microwave assisted method, it was proved that the microwave assisted method is convenient for synthesis of this type of 2,5-di-substituted 1,3,4-oxadiazole 6a-o.

Info:

Periodical:
International Letters of Chemistry, Physics and Astronomy (Volume 30)
Pages:
159-166
DOI:
10.18052/www.scipress.com/ILCPA.30.159
Citation:
D. L. Namera and U. C. Bhoya, "Convenient Synthesis of the 2,5-di-Substituted 1,3,4-Oxadiazole Derivatives under Microwave", International Letters of Chemistry, Physics and Astronomy, Vol. 30, pp. 159-166, 2014
Online since:
Mar 2014
Export:
Distribution: