A new series of 2,5-distyryl-1,3,4-oxadiazoles derivatives have been synthesized from cinnamic hydrazide on reaction with various cinnamic acid derivatives. The structures of synthesized compounds have been elucidated by spectral studies like IR, 1HNMR, Mass and also Elemental Analysis. Furthermore, all synthesized compounds were screened for In Vitro anti microbial activity against the gram positive (Staphylococcus aureus, Pseudomonas aeruginosa) and gram negative (Escherichia coli) bacterial strain. In which some the compounds show potential inhibition against the test organisms.
International Letters of Chemistry, Physics and Astronomy (Volume 29)
D. L. Namera et al., "Microwave Assisted Synthesis of 2,5-Distyryl-1,3,4-Oxadiazole Derivatives as Anti Microbial Agents", International Letters of Chemistry, Physics and Astronomy, Vol. 29, pp. 46-54, 2014