Antibacterial, Antifungal, Anti-Oxidant, Anti-Inflammatory and Anti-Hypertensive Activities of N-Chloropyrazinamide

Vaijayanthi, S. Parimala; Mathiyalagan, N.

doi:10.18052/www.scipress.com/ILCPA.26.1

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Antibacterial, Antifungal, Anti-Oxidant, Anti-Inflammatory and Anti-Hypertensive Activities of N-Chloropyrazinamide

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Abstract:

N-chloropyrazinamide was prepared by the chlorination of pyrazinamide using trichloroisocyanuric acid. The experimental results ascertained that the tested N-chloropyrazinamide showed good antimicrobial activities when compared to standard drug. It was found that N-chloropyrazinamide at different concentrations exhibited significant dose dependent anti-oxidant, anti-inflammatory and anti-hypertensive activity.

Info:

Periodical:

International Letters of Chemistry, Physics and Astronomy (Volume 26)

Pages:

1-8

DOI:

https://doi.org/10.18052/www.scipress.com/ILCPA.26.1

Citation:

S. P. Vaijayanthi and N. Mathiyalagan, "Antibacterial, Antifungal, Anti-Oxidant, Anti-Inflammatory and Anti-Hypertensive Activities of N-Chloropyrazinamide", International Letters of Chemistry, Physics and Astronomy, Vol. 26, pp. 1-8, 2014

Online since:

January 2014

Authors:

S. Parimala Vaijayanthi, N. Mathiyalagan

Keywords:

Antibacterial Activity, Antifungal Activity, Antihypertensive Activity, Anti-Inflammatory, Anti-Oxidant Activity, N-Chloropyrazinamide

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Creative Commons Attribution 4.0 International License

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[2] P. Mech, M. Makowski, A. Kawiak, A. Chylewska, "When biomolecules meet 2-hydrazinopyrazine: from theory through experiment to molecular levels using a wide spectrum of techniques", RSC Advances, Vol. 10, p. 40673, 2020

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[3] M. Abd ul‐Malik, A. Kamal El‐Dean, S. Radwan, R. Zaki, " Facile synthesis and antimicrobial evaluations of some novel pyrazolo[3,4‐ b ]selenolo[3,2‐ e ]pyrazines and their related heterocycles ", Journal of Heterocyclic Chemistry, 2021

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