N-chloropyrazinamide was prepared by the chlorination of pyrazinamide using trichloroisocyanuric acid. The experimental results ascertained that the tested N-chloropyrazinamide showed good antimicrobial activities when compared to standard drug. It was found that N-chloropyrazinamide at different concentrations exhibited significant dose dependent anti-oxidant, anti-inflammatory and anti-hypertensive activity.
International Letters of Chemistry, Physics and Astronomy (Volume 26)
S. P. Vaijayanthi and N. Mathiyalagan, "Antibacterial, Antifungal, Anti-Oxidant, Anti-Inflammatory and Anti-Hypertensive Activities of N-Chloropyrazinamide", International Letters of Chemistry, Physics and Astronomy, Vol. 26, pp. 1-8, 2014