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Synthesis and Antimicrobial Screening of some New Pyrimido[1,2-a]Benzimidazole Derivatives

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Abstract:

Some new pyrimido[1,2-a]benzimidazole derivatives were synthesized by reacting 2-amino benzimidazole and chalcones in n-butanol at reflux temperature. In our present study we have used various heterocyclic chalcones derived from furfural and substituted acetophenones. All synthesized compounds were characterized by IR, 1H NMR and Mass spectroscopy. All synthesized compounds were screened for their antimicrobial activity against gram positive and gram negative bacteria which showed moderate to good activity.

Info:

Periodical:
International Letters of Chemistry, Physics and Astronomy (Volume 25)
Pages:
56-60
DOI:
10.18052/www.scipress.com/ILCPA.25.56
Citation:
N. M. Shah and H. S. Joshi, "Synthesis and Antimicrobial Screening of some New Pyrimido[1,2-a]Benzimidazole Derivatives", International Letters of Chemistry, Physics and Astronomy, Vol. 25, pp. 56-60, 2014
Online since:
Jan 2014
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