The wide spread use of 1,3,4-oxadiazoles as a scaffold in medicinal chemistry establishes this moiety as an important bioactive class of heterocycles. In the present study ultrasonic velocity (u), density (ρ) and viscosity (η) have been measured at frequency 2 MHz in the binary mixtures of 1,3,4-oxadiazole derivatives in acetone at 303.15 K using ultrasonic interferometer technique. The measured value of ultrasonic velocity, density and viscosity have been used to estimate the acoustical parameters namely adiabatic compressibility (βad), relaxation time (τ), acoustic impedance (Zi), free length (Lf), free volume (Vf) and internal pressure (πi), with a view to investigate the nature and strength of molecular interactions. The obtained result support the occurrence of molecular association through hydrogen bonding in the binary liquid mixtures.
International Letters of Chemistry, Physics and Astronomy (Volume 24)
G. Alamelumangai and N. Santhi, "Acoustical Studies on Binary Liquid Mixtures of Some 1,3,4-Oxadiazole Derivatives with Acetone at 303.15 K", International Letters of Chemistry, Physics and Astronomy, Vol. 24, pp. 124-133, 2014