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Aryl Chalcones as Efficient Precursors for Deriving Oxazine: Solvent-Free Synthesis and Antimicrobial Activities of some Oxazine-2-amines

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Abstract:

A series of some oxazine derivatives has been synthesised by fly-ash:H2SO4 catalyzed solvent-free cyclization of aryl chalcones and urea under microwave irradiation. The yields of the oxazines were more than 85%. The synthesised oxazines were characterized by their physical constants, analytical and spectroscopic data. The antimicrobial activities of these oxazines have been studied using Bauer-Kirby method.

Info:

Periodical:
International Letters of Chemistry, Physics and Astronomy (Volume 23)
Pages:
82-97
DOI:
https://doi.org/10.18052/www.scipress.com/ILCPA.23.82
Citation:
G. Thirunarayanan et al., "Aryl Chalcones as Efficient Precursors for Deriving Oxazine: Solvent-Free Synthesis and Antimicrobial Activities of some Oxazine-2-amines", International Letters of Chemistry, Physics and Astronomy, Vol. 23, pp. 82-97, 2014
Online since:
Nov 2013
Authors:
Ganesamoorthy Thirunarayanan, R. Sundararajan, R. Arulkumaran
Keywords:
Antimicrobial Activities, Chalcones, Environmentally Benign Reaction, Fly-Ash: H2SO4, Oxazine Amines
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Distribution:
Open Access

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This work is licensed under a
Creative Commons Attribution 4.0 International License

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