Spectral Correlation Analysis and Antimicrobial Activities of some 2,4-Dimethoxy Phenyl Chalcones

John Joseph, S.; Arulkumaran, R.; Kamalakkannan, D.; Sakthinathan, S.P.; Sundararajan, R.; Suresh, R.; Vijayakumar, S.; Ranganathan, K.; Kalyanasundaram, N.; Vanangamudi, Ganesan; Thirunarayanan, Ganesamoorthy

doi:10.18052/www.scipress.com/ILCPA.23.48

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Spectral Correlation Analysis and Antimicrobial Activities of some 2,4-Dimethoxy Phenyl Chalcones

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Abstract:

A series of 2,4-dimethoxy phenyl chalcones have been synthesized by Crossed-Aldol condensation of 2,4-dimethoxy phenyl and various substituted benzaldehydes. The purities of these chalcones have been checked by their physical constants, UV, IR, NMR and MASS spectral data. The spectral data of these chalcones have been correlated with Hammett sigma constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effects of substituents on the spectral group frequencies have been discussed. The anti-microbial activities of these chalcones have been evaluated using Bauer-Kirby method.

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Periodical:

International Letters of Chemistry, Physics and Astronomy (Volume 23)

Pages:

48-65

DOI:

https://doi.org/10.18052/www.scipress.com/ILCPA.23.48

Citation:

S. John Joseph et al., "Spectral Correlation Analysis and Antimicrobial Activities of some 2,4-Dimethoxy Phenyl Chalcones", International Letters of Chemistry, Physics and Astronomy, Vol. 23, pp. 48-65, 2014

Online since:

November 2013

Authors:

S. John Joseph, R. Arulkumaran, D. Kamalakkannan, S.P. Sakthinathan, R. Sundararajan, R. Suresh, S. Vijayakumar, K. Ranganathan, N. Kalyanasundaram, Ganesan Vanangamudi, Ganesamoorthy Thirunarayanan

Keywords:

Antimicrobial Activities, IR Spectra, NMR Spectra, Substituent Effects, Substituted Styryl 2,4-Dimethoxy Phenyl Ketones, UV Spectra

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References:

Thirunarayanan G., Vanangamudi G., Subramanian M., Organic Chem: An Indian J. 9(1) (2013) 1-16.

Janaki P., Sekar K. G., Thirunarayanan G., J. Saudi Chem. Soc. 2013, Accepted and in press. DOI: org/10. 1016/j. jscs. 2012. 11. 013.

Holla B. S., Akberali P. M., Shivananda M. K., IL Farmaco 55 (2000) 256-261.

Venkat Reddy G., Maitraie D., Narsaiah B., Rambabu Y., ShanthanRao P., Synth. Commun 31(18) (2004) 2882-2884.

Orsini F., Sello G., Fumagalli T., Synlett. (2006), 1717-1718.

Vanangamudi G., Subramanian S., Jayanthi P., Arulkumaran R., Kamalakkannan D., Thirunarayanan G., Arab. J. Chem., 201, DOI: 10. 1016/j. arabjc. 2010. 07. 019.

Tran T. D., Park H., Ecker G. F., Thai K. M., 2, 3'-Hydroxychalcone Analogues: Synthesis and Structure-PGE2 Inhibitory Activity Relationship, 12th International Electronic Conference on Synthetic Organic Chemistry (ECSOC-12) 1-30 November 2008; http: /www. usc. es/congresos/ecsoc/12/ECSOC12. htm &http: /www. mdpi. org/ecsoc-12 No. C0011, pp.1-7.

Mohan S. B., Behera T. P., Ravi Kumar B. V. V., Int. J. ChemTech. Res. 2(3) 2010 1634-1637.

Thirunarayanan G., Vanangamudi G., Arkivoc. 12 (2006) 58-64.

Thirunarayanan G., Ananthakrishna Nadar P., J. Indian Chem. Soc. 83(11) (2006) 11071112.

Ballini R., Bosica G., Maggi R., Ricciutelli M., Righi P., Sartori G., Sartorio R., Green Chem. 3 (2001) 178-180.

Solhy A., Tahir R., Sebti S. Skouta R., Bousmina M., Zahouily M., Larzek M., Appl. Catal. A: General. 374 (2010) 189-193.

Thirunarayanan G., J. Indian Chem. Soc. 84 (2008) 447-451.

Basaif S. A., Sobahi T. R., Khalil A. K., Hassan M. A., Bulletin of the Korean Chem. Soc. 26(11) (2005) 1677-1681.

Xu Q., Yang Z., Yin D., Zhang F., Catal. Commun. 9(1) (2008) 1579-1582.

Kumar P., Kumar S., Husain K., Kumar A., Bioorg. Med. Chem. 18(14) (2010) 49654974.

Zhang Z., Dong Y., W., Wang G. W., Chem. Lett. 32(10) (2003) 966-967.

Thirunarayanan G., IUP. J. Chem. 3(4) (2010) 35-54.

Thirunarayanan G., et al., Elixir Org. Chem. 45 (2012) 7898-7905.

Thirunarayanan G., Mayavel P., Thirumurthy K., Spectrochimica Acta. 91A (2012) 1822.

Sundararajan R., et al., Int. J. Pharm. Chem. Sci. 1(4) (2012) 1657-1677.

Thirunarayanan G., Surya S., Srinivasan S., Vanangamudi G., Sathiyendiran V., Spectrochim. Acta. 75A (2010) 152-156.

Janaki P., Sekar K. G., Thirunarayanan G., Org. Chem: An Indian J. 9(2) (2013) 68-80.

Arulkumaran R., Vijayakumar S., Sundararajan R., Sakthinathan S. P., Kamalakkannan D., Suresh R., Ranganathan K., Vanangamudi G., Thirunarayanan G., International Letters of Chemistry, Physics and Astronomy 4 (2012) 17-38.

Kamalakkannan D, Vanangamudi G, Arulkumaran R, Thirumurthy K, Mayavel P, Thirunarayanan G, Elixir Org. Chem., 46, 2012, 8157-8166.

Sivakumar M., PhrabuSreeneivasan S., Kumar V., Doble M., Bioorg. Med Chem. Lett. 17(10) (2007) 3169-3172.

Liu X., Go M. L., Bioorg. Med. Chem. 14(1) (2006) 153-163.

Arulkumaran R, et al., IUP J. Chem. 3(1) (2010) 82-98.

Deng J., Sanchez T., Lalith Q. A. M., Bioorg. Med. Chem. 15(14) (2007) 4985-5002.

Bauer A. W., Kirby W. M. M., Sherris J. C., Truck M., Am. J. Clin. Pathol. 45 (1966) 493-496.

Thirunarayanan G., Fly-ash: H2O Assisted Aldol Condensation: Effect of Solvents on the Synthesis of Some Aryl (E) 2-propen-1-ones, Accepted article in Annales, UMCS Chem. J., (2013).

Marquardt F. H., Helv. Chim. Acta. 48 (7) (1965) 1476-1485.

Liu Xiaoling, Bioorg. Med. Chem. 14(1) (2006) 153-163.

Buu-Hoi Ng. Ph., J. Org. Chem. 22 (1957) 193-7.

Vandrewala H. P., J. Univ. Bom Sci: Phys Sci, Math, Biol. Sci. Med. 16 (1948) 43-5.

Kauffmann Hugo, Ber. Dtsch. Chem. Ges. 54B (1921) 795-802.

Swain C. G., Lupton Jr. E. C., J. Am. Chem. Soc. 90(16) (1968) 4328-4337.

Deiva C. M., Pappano N. B., Debattisata N. B., Rev. Microbiol. 29(4) (1998) 307-310.

Thirunarayanan G., J. Saudi Chem. Soc., 2011. DOI: 10. 1016/j. jscs. 2011. 12. 003.

K. Ranganathan, R. Suresh, D. Kamalakkannan, R. Arulkumaran, R. Sundararajan, S. P. Sakthinathan, S. Vijayakumar, G. Vanangamudi, K. Thirumurthy, P. Mayavel, G. Thirunarayanan, International Letters of Chemistry, Physics and Astronomy 4 (2012).

R. Arulkumaran, S. Vijayakumar, R. Sundararajan, S. P. Sakthinathan, D. Kamalakkannan, R. Suresh, K. Ranganathan, P. R. Rajakumar, G. Vanangamudi, G. Thirunarayanan, International Letters of Chemistry, Physics and Astronomy 5 (2013) 21-38.

S. Vijayakumar, R. Arulkumaran, R. Sundararajan, S. P. Sakthinathan, R. Suresh, D. Kamalakkannan, K. Ranganathan, K. Sathiyamoorthy, V. Mala, G. Vanangamudi, G. Thirunarayanan, International Letters of Chemistry, Physics and Astronomy 9(1) (2013).

Thirunarayanan G., Sekar K. G., International Letters of Chemistry, Physics and Astronomy 10 (2013) 18-34.

R. Sundararajan, R. Arulkumaran, S. Vijayakumar, D. Kamalakkannan, R. Suresh, S. John Joseph, K. Ranganathan, S. P. Sakthinathan, G. Vanangamudi, G. Thirunarayanan, International Letters of Chemistry, Physics and Astronomy 1 (2014).

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