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International Letters of Chemistry, Physics and Astronomy
Volume 14
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Scavenging Activity, Anti-Inflammatory and Diabetes Related Enzyme Inhibition Properties of Leaves Extract from some Varieties of Phoenyx dactylifera l.

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Abstract:

In this study we investigate the antioxidant, anti-inflammatory, and antidiabetic activities of ethanolic leaves extracts of three selected varieties of Phoenyx dactylifera L. namely: “Ghars”, “Deglet Nour” and “Hamraya”. The assessment of the antioxidant potential of crude leaves extracts, using superoxide anions inhibition, DPPH and total antioxidant activity essays, was carried out. Furthermore, the anti-inflammatory properties of the extracts were determined by measuring the inhibition of nitric oxide (NO) production. Moreover, the antidiabetic effect was evaluated by inhibition of α-amylase enzymes. The total phenolic content measured by Folin-Ciocalteu method was as well conducted. The raw leaves extracts of the selected varieties was found to contain a high content of total phenolic content (342.45 mg GAE/gDW for GE) and therefore exhibited a higher antioxidant activity and inhibitory effect of radicals scavenging activity against DPPH and superoxide anion (IC50 = 7.44 μg/mL and 39.11 μg/mL respectively). The three varieties exhibited significant inhibition nitric oxide using In Vitro assay (IC50 = 240.28 μg/mL for GE). The extracts also displayed high inhibition actions against α-amylase enzymes. The results suggest that the leaves of the three selected varieties of Phoenyx dactylifera can be considered as a good source of natural antioxidant and anti-inflammation drugs as well as potent antidiabetic medicine.

Info:

Periodical:
International Letters of Chemistry, Physics and Astronomy (Volume 14)
Pages:
125-135
Citation:
L. S. Eddine et al., "Scavenging Activity, Anti-Inflammatory and Diabetes Related Enzyme Inhibition Properties of Leaves Extract from some Varieties of Phoenyx dactylifera l.", International Letters of Chemistry, Physics and Astronomy, Vol. 14, pp. 125-135, 2013
Online since:
May 2013
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Al Farsi M. A, Lee C. Y., Crit. Rev. Food Sci 48 (2008) 877-887.

Dowson V. H. W., FAO Food and Agriculture Organisation of the United Nations. Paper No 35. Rome (1982).

Baliga M. S., Vitttaldas Baliga B. R., Kandathil S. M, Bhat H. P., Vayalil P. K., Food Res. Int. 44 (2011) 1812-1822.

Al-Shahib W., Marshall R. J., Int. J. Food . Sci. Nutr. 54 (2003) 247-259.

Chandra M., Riley M. G., Johnson D. E., Arch. Toxicol. 66 (1992) 496-502.

Ahmed A. I., Ahmed A. W. K., Robinson R. K., Food Chem. 45 (1995) 305-309.

Thomas M., Emilie D., Gaëtan Le. F., Marie E. L., Claire E., Food Chem. 131 (2012) 754-760.

Rubem C. H., Vera Maria F. V., Mutag 18 (2003) 113-118.

Hossain M. A., Rahman S. M. M., Food Res. Int. 44 (2011) 672-676.

Pandhair V., Sekhon B. S., J. Plant Biochem. Biotechnol. 15 (2006) 71-78.

Mayer R., Stecher G., Wuerzner R., Silva R. C., Sultana T., Trojer L., et al, J. Agri. Food Chem. 56 (2008) 6959-6966.

Saleem M., Nazir M., Ali M. S., Hussain H., Lee Y. S., Riaz N., et al, Nat Prod Rep 27 (2012) 238-254.

Pietta P. G., J. Nat. Prod. 63 (2000) 1035-1042.

Rice-Evans C. A., Miller N. J., Pacanga G., Trens plant Sc. i 2 (1997) 152-159.

Edziri H., Ammar S., Souad L., Mahjoub M. A., Mastouri M., Aouni M., et al, S. Afr. J. Bot. 78 (2012) 252-256.

Maria A., Harris P., Dimitris K., Alexio-Leandros S., Serkos A. H., Food Sci. Technol. Int. 48 (2012) 316-322.

Proestos C., Sereli D., Komaitis M., Food Chem. 95 (2006) 44-52.

Terao K., Ohmori S., Igarashi K., Ohtani I., Watanabe M. F., Harada K.I., et al, Toxicon. 32 (1994) 833-843.

Sweetie R. K., Arjun K., Arun S., Food Res. Int. 44 (2011) 3182-3187.

Sunday O. O., Anthony J. A., Asian Pac. J. Trop. Med. 4 (2011) 952-958.

Neha B., Harinder S. O., Dewinder S. U., Ramabhau T. P., Food Res. Int. 44 (2011) 391-396.

Jonathan D. A., Esther G. S., Esperanza V. S., David G. G., Food Control 24 (2012) 136-141.

Singleton V. L., Rossi J. A. Jr., Am J Enol. Viticult 16 (1965) 144-158.

Shaofang L., Jie S., Lina Y., Chushu Z., Jie B., Feng Z., et al, Food Chem. 134 (2012) 1885-1891.

Hanato T., Kagawa H., Yasuhara T., Okuda T., Chem. Pharma. Bull. 36 (1988) 2090-(2097).

Falleh H., Ksouri R., Oueslati S., Guyot S., Magné C., Abdelly C., Food. Chem. Toxicol. 47 (2009) 2308-2313.

Kilani-Jaziri S., Bhouri W., Skandrani I., Limem I., Chekir-Ghedira L., Ghedira K., South African Journal of Botany 77 (2011) 767-776.

Praveen K. Vayalil, J. Agric. Food Chem. 50 (2002) 610-617.

Christudas S., Paul A., Chidambarm K., Savarimuthu I., Food. Chem. Toxicol. 50 (2012) 1547-1553.

Mbaebie B. O., Edeoga H.O., Afolayan A. J., Asian Pac. J. Trop Biomed 2 (2012) 118-124.

Qing-Feng Z., Yu-Xian G., Xinchen S., Guodong Z., Wen-Jun W., Food Chem. 133 (2012) 140-145.

Catherin N. K., Jasper K. I., Michael W. O., Hans K. B., Food Sci. Technol. 45 (2012) 269-276.

Dhaouadi K., Raboudi F., Estevan K., Barrajon E., Vilanova E., Hamdaoui M., et al, J. Agric. Food Chem. 59 (2011) 402-406.

Manjeshwar S. B., Bantwal Raghavendra V. B., Shaun M. K., Harshith P. B., Praveen K. V., Food Res. Int. 44 (2011) 1812-1822.

Chaira N., Smaali M. I., Martinez-Tome M., Mrabet A., Murcia M. A., Ferchichi A., Int. J. Food Sci. Nutr. 60 (2009) 316-329.

Tahraoui A., El-Hilaly J., Israili Z. H., Lyoussi B., J. Ethnopharmacol 110 (2007) 105-117.

Doha M. A., Al-Okbi S. Y., Pol. J. Food Nutr. Sci. 13 (2004) 397-402.

Loganayaki N., Siddhurajub P., Manian S., J. Ethnopharmacol 140 (2012) 230-233.

Ruch R. J., Cheng S. J., Klaunig J.E., Carcinogens 10 (1989) 1003-1008.

Motar M. L. R., Thomas G., Barbose Fillo J. M., J. Ethnopharmacol 95 (1985) 139-142.

Olayinka A. Aiyegoro, Anthony I. Okoh, BMC Complement Altern. Med. 10(21) (2010) 1-8.

Edenharder R., Grunhage D., Mutat. Res. 540 (2003) 1-18.

Park K. Y., Jung G. O., Lee K. T., Choi J., Choi M. Y., Kim G. T., et al, J. Ethnopharmacol 90 (2004) 73-79.

Indrajit K., Narayan D., Pathik S., Nilanjan S., Asis B., Pallab K. H., Orient Pharm Exp. Med. 11 (2011) 221-228.

Kundu S., Bala A., Ghosh P., Mukhopadhya D., Mitra A., Sarkar A., et al, Free Radic. Res. 45 (2011) 518-526.

Duenas M., Hernandez T., Estrella I., Food Chem. 98 (2006) 95-103.

Jiang F., Dusting G. J., Curr. Vasc. Pharmacol 1 (2003) 135-156.

Randhir R., Kwon Y. I., Shetty K., Innovat Food. Sci Emerg. Tech. 9 (2008) 355-364.

Chethan S., Sreerama Y. N., Malleshi N. G., Food Chem. 111 (2008) 187-191.

Qi Y., Feng C., Xi W., Yueming J., Songyi L., LWT - Food Sci. Technol. 46 (2012) 164-168. ( Received 04 May 2013; accepted 08 May 2013 ).

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Cited By:

[1] N. Abdul-Hamid, M. Maulidiani, A. Mediani, U. Yahya, I. Ismail, C. Tham, K. Shadid, F. Abas, "Physicochemical characteristics, nutritional composition, and phytochemical profiles of nine Algerian date palm fruit (Phoenix dactylifera L.) varieties", Journal of Food Biochemistry, p. e12663, 2018

DOI: https://doi.org/10.1111/jfbc.12663