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Spectral Correlations and Antimicrobial Activities of some 1-Pyrenyl Chalcones
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Spectral Correlations and Antimicrobial Activities of some 1-Pyrenyl Chalcones

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Abstract:

A series of 1-pyrenyl chalcones have been synthesized by Crossed-Aldol condensation of 1-acetylpyrene and substituted benzaldehydes. The purities of these chalcones have been checked by their physical constants, UV, IR, NMR and MASS spectral data. The spectral data of these chalcones have been correlated with Hammett sigma constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effect of substituents on the spectral group frequencies have been discussed. The anti-microbial activities of these chalcones have been evaluated using Bauer-Kirby method.

Info:

Periodical:
International Letters of Chemistry, Physics and Astronomy (Volume 10)
Pages:
21-38
DOI:
https://doi.org/10.18052/www.scipress.com/ILCPA.10.21
Citation:
R. Arulkumaran et al., "Spectral Correlations and Antimicrobial Activities of some 1-Pyrenyl Chalcones", International Letters of Chemistry, Physics and Astronomy, Vol. 10, pp. 21-38, 2013
Online since:
September 2013
Authors:
R. Arulkumaran, S. Vijayakumar, R. Sundararajan, S.P. Sakthinathan, D. Kamalakkannan, R. Suresh, K. Ranganathan, P.R. Rajakumar, Ganesan Vanangamudi, Ganesamoorthy Thirunarayanan
Keywords:
Antimicrobial Activities, IR Spectra, NMR Spectra, Substituent Effects, Substituted Styryl 1-Pyrenyl Ketones, UV Spectra
Export:
RIS, BibTeX, Text
Distribution:
Open Access

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This work is licensed under a
Creative Commons Attribution 4.0 International License

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