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Spectral Correlations and Antimicrobial Activities of some 1-Pyrenyl Chalcones

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Abstract:

A series of 1-pyrenyl chalcones have been synthesized by Crossed-Aldol condensation of 1-acetylpyrene and substituted benzaldehydes. The purities of these chalcones have been checked by their physical constants, UV, IR, NMR and MASS spectral data. The spectral data of these chalcones have been correlated with Hammett sigma constants, F and R parameters using single and multi-linear regression analysis. From the results of statistical analysis, the effect of substituents on the spectral group frequencies have been discussed. The anti-microbial activities of these chalcones have been evaluated using Bauer-Kirby method.

Info:

Periodical:
International Letters of Chemistry, Physics and Astronomy (Volume 10)
Pages:
21-38
DOI:
https://doi.org/10.18052/www.scipress.com/ILCPA.10.21
Citation:
R. Arulkumaran et al., "Spectral Correlations and Antimicrobial Activities of some 1-Pyrenyl Chalcones", International Letters of Chemistry, Physics and Astronomy, Vol. 10, pp. 21-38, 2013
Online since:
Sep 2013
Authors:
R. Arulkumaran, S. Vijayakumar, R. Sundararajan, S.P. Sakthinathan, D. Kamalakkannan, R. Suresh, K. Ranganathan, P.R. Rajakumar, Ganesan Vanangamudi, Ganesamoorthy Thirunarayanan
Keywords:
Antimicrobial Activities, IR Spectra, NMR Spectra, Substituent Effects, Substituted Styryl 1-Pyrenyl Ketones, UV Spectra
Export:
RIS, BibTeX, Text
Distribution:
Open Access

Creative Commons License
This work is licensed under a
Creative Commons Attribution 4.0 International License

References:

[1] Thirunarayanan G., Vanangamudi G., Subramanian M., Organic Chem: An Indian J. 9(1), (2013) 1-16.

[2] Janaki P., Sekar K. G., Thirunarayanan G., J. Saudi Chem. Soc., 2013, Accepted and in press. DOI: org/10. 1016/j. jscs. 2012. 11. 013.

[3] Holla B. S., Akberali P. M., Shivananda M. K., IL Farmaco 55 (2000) 256-261.

DOI: https://doi.org/10.1016/s0014-827x(00)00030-6

[4] Venkat Reddy G., Maitraie D., Narsaiah B., Rambabu Y., Shanthan Rao P., Synth. Commun 31(18), (2004) 2882-2884.

[5] Orsini F., Sello G., Fumagalli T., Synlett. 11 (2006) 1717-1718.

[6] Vanangamudi G., Subramanian S., Jayanthi P., Arulkumaran R., Kamalakkannan D., Thirunarayanan G., Arab. J. Chem., 2010, DOI: 10. 1016/j. arabjc. 2010. 07. 019.

[7] Tran T. D., Park H., Ecker G. F., Thai K. M., 12th International Electronic Conference on Synthetic Organic Chemistry (ECSOC-12), 1-30 November 2008; http: /www. usc. es/congresos/ecsoc/12/ECSOC12. htm & http: /www. mdpi. org/ecsoc-12 No. C0011, pp.1-7.

DOI: https://doi.org/10.1039/b108029f

[8] Mohan S. B., Behera T. P., Ravi Kumar B. V. V., Int. J. ChemTech. Res. 2(3), (2010) 1634-1637.

[9] Thirunarayanan G., Vanangamudi G., Arkivoc. 12 (2006) 58-64.

[10] Thirunarayanan G., Ananthakrishna Nadar P., J. Indian Chem. Soc. 83(11), (2006) 1107-1112.

[11] Ballini R., Bosica G., Maggi R., Ricciutelli M., Righi P., Sartori G., Sartorio R., Green Chem. 3 (2001) 178-180.

DOI: https://doi.org/10.1039/b101355f

[12] Solhy A., Tahir R., Sebti S., Skouta R., Bousmina M., Zahouily M., Larzek M., Appl. Catal. A: General. 374 (2010) 189-193.

DOI: https://doi.org/10.1016/j.apcata.2009.12.008

[13] Thirunarayanan G., J. Indian Chem. Soc. 84 (2008) 447-451.

[14] Basaif S. A., Sobahi T. R., Khalil A. K., Hassan M. A., Bulletin of the Korean Chem. Soc. 26(11) (2005) 1677-1681.

[15] Xu Q., Yang Z., Yin D., Zhang F., Catal. Commun. 9(1) (2008) 1579-1582.

[16] Kumar P., Kumar S., Husain K., Kumar A., Bioorg. Med. Chem. 18(14) (2010) 4965-4974.

[17] Zhang Z., Dong Y. W., Wang G. W., Chem. Lett. 32(10), (2003) 966-967.

[18] Thirunarayanan G., IUP. J. Chem. 3(4) (2010) 35-54.

[19] Thirunarayanan G., Thirumurthy K., Vanangamudi G., Subramanian M., Arulkumaran R., Kamalakkannan D., Sundararajan R., Sakthinathan S. P., Vijayakumar S., Ranganathan K., Suresh R., Elixir Org. Chem. 45 (2012) 7898-7905.

DOI: https://doi.org/10.1016/j.saa.2012.09.039

[20] Thirunarayanan G., Mayavel P., Thirumurthy K., Spectrochimica Acta. 91A (2012) 18-22.

[21] Sundararajan R., Arulkumaran R., Vijayakumar S., Kamalakkannan D., Suresh R., Ranganathan K., Sakthinathan S. P., Vanangamudi G., Thirumurthy K., Mayavel P., Thirunarayanan G., Int. J. Pharm. Chem. Sci. 1(4) (2012) 1657-1677.

DOI: https://doi.org/10.1016/j.saa.2012.09.039

[22] Thirunarayanan G., Surya S., Srinivasan S., Vanangamudi G., Sathiyendiran V., Spectrochim. Acta. 75A (2010) 152-156.

[23] Janaki P., Sekar K. G., Thirunarayanan G., Org. Chem: An Indian J. 9(2) (2013) 68-80.

[24] Arulkumaran R., Vijayakumar S., Sundararajan R., Sakthinathan S. P., Kamalakkannan D., Suresh R., Ranganathan K., Vanangamudi G., Thirunarayanan G., Int. Lett. Chem. Phys. Astro. 4 (2012) 17-38.

DOI: https://doi.org/10.18052/www.scipress.com/ilcpa.4.17

[25] Kamalakkannan D., Vanangamudi G., Arulkumaran R., Thirumurthy K., Mayavel P., Thirunarayanan G., Elixir Org. Chem. 46 (2012) 8157-8166.

[26] Sivakumar M., Phrabu Sreeneivasan S., Kumar V., Doble M., Bioorg. Med. Chem. Lett. 17(10) (2007) 3169-3172.

[27] Liu X., Go M. L., Bioorg. Med. Chem. 14(1) (2006) 153-163.

[28] Arulkumaran R., Sundararajan R., Vanangamudi G., Subramanian M., Ravi K., Sathiyendidran V., Srinivasan S., Thirunarayanan G., IUP J. Chem. 3(1) (2010) 82-98.

[29] Deng J., Sanchez T., Lalith Q. A. M., Bioorg, Med. Chem. 15(14) (2007) 4985-5002.

[30] Bauer A. W., Kirby W. M. M., Sherris J. C., Truck M., Am. J. Clin. Pathol. 45 (1966) 493-496.

[31] Thirunarayanan G., Fly-ash: H2O Assisted Aldol Condensation: Effect of Solvents on the Synthesis of Some Aryl (E) 2-propen-1-ones, Accepted article in Annales, UMCS Chem. J., (2013).

DOI: https://doi.org/10.2478/v10063-012-0004-7

[32] Ranganathan K., Suresh R., Kamalakkannan D., Arulkumaran R., Sundararajan R., Sakthinathan S. P., Vijayakumar S., Vanangamudi G., Thirumurthy K., Mayavel P., Thirunarayanan G., Int. Lett. Chem. Phys. Astro. 4 (2012) 66-75.

DOI: https://doi.org/10.18052/www.scipress.com/ilcpa.4.66

[33] Swain C. G., Lupton Jr. E. C., J. Am. Chem. Soc. 90(16) (1968) 4328-4337.

[34] Deiva C. M., Pappano N. B., Debattisata N. B., Rev. Microbiol. 29(4) (1998) 307-310.

[35] Lahtchev K. L., Batovska D. I., St Parushev P., Ubiyvock V. M., Sibirny A. A., Eur. J. Med. Chem. 43(1) (2008) 2220-2228.

[36] Weber M. W, Hunsaker L. A., Abcouwer S. F., Decker L. M., Vander D. L. Jagat, Bioorg. Med. Chem. 13 (2005) 3811-3820.

[37] Dominguez J. N., Leon C., Rodrigues J., IL Farmaco. 60(4) (2005) 307-311.

[38] Lin Y. M., Zhon Y., Flavin M. T., Zhon L. M., Ne W., Chen F. C., Bioorg. Med. Chem. 10(8) (2002) 2795-2802.

[39] Liu X., Go M. L., Bioorg. Med. Chem. 14 (2006) 153-163.

[40] Delmulle L., Bellahcene A., Dhooge W., Comhaire F., Roelens F., Huvaere K., Heyerick A., Castronovo V., Keukeleire D. D., Phytomed. 13 (2006) 732-734.

DOI: https://doi.org/10.1016/j.phymed.2006.01.001

[41] Nielsen S. F., Chen M., Theander T. G., Kharazmi A., Christensen S. B., Bioorg. Med. Chem. Lett. 5 (1995) 449-452.

[42] Thirunarayanan G., J. Saudi Chem. Soc., 2011. DOI: 10. 1016/j. jscs. 2011. 12. 003.

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