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 R. Davicino et al., Different activities of Schinus areira L.: anti-inflammatory or pro-inflammatory effect, Immunopharmacol. Immunotoxicol. 32(4) (2010) 620-627.
 A. N, Shikov et al., Anti-inflammatory effect of Pinus sibirica oil extract in animal models, J. Nat. Med. 62 (2008) 436–440.
 S. Ahmad et al., Synthesis and biological evaluation of some novel 6-aryl-2-(p-sulfamylphenyl)-4, 5-dihydropyridazin-3(2H)-ones as anti-cancer, antimicrobial, and anti-inflammatory agents, J. Enzyme Inhib. Med. Chem. 25 (2010) 266–271.
 A.G. Habeeb, P.N. Praveen Rao, E.E. Knaus, Design and Synthesis of Celecoxib and Rofecoxib Analogues as Selective Cyclooxygenase-2 (COX-2) Inhibitors: Replacement of Sulfonamide and Methylsulfonyl Pharmacophores by an Azido Bioisostere, J. Med. Chem. 44 (2001).
 A. Casini, A. Scozzafava, C.T. Supuran, Sulfonamide derivatives with protease inhibitory action as anticancer, anti-inflammatory and antiviral agents, Exp. Opin. Ther. Pat. 12 (2002) 1307-1327.DOI: https://doi.org/10.1517/135437126.96.36.1997
 A. Kołaczek et al., Biological activity and synthesis of sulfonamide derivatives: a brief review, Chemik. 68 (2014) 620–628.
 N. Anand, Sulfonamides and Sulfons, In M.E. Wolff (Ed. ), Burger's Medicinal Chemistry, Vol. 2, 5th ed, New York, Wiley- Interscience, 1996, Chapter 33.
 C.B.C. Ikpa, U.C. Okoro, Synthesis of new paratoluene sulphonamide derivatives of amino acids and their anti bacterial activities, IOSR Journal of Applied Chemistry. 9 (6) (Ver. II) (2016) 31-34.
 J.W. Ward, J.R. Elsea, Animal case and use in drug fate and metabolism, In: R.G. Edward, L.H. Jean, (Eds), Methods and Techniques, 1st edi. New York, Markel Dekker, (1997).
 Organization for Economic Cooperation and Development, OECD guidelines for the testing of chemicals, acute oral toxicity - up-and down procedure, No. 425. Paris, Organization for Economic Cooperation and Development, 2008. [Online] Available from: http: /www. oecd-ilibrary. org/docserver/download/9742501e. pdf?expires=1437730561&id=id&accname=guest&checksum=0B6C86B8F1B2E751997E5F54CFDF8F5E [Accessed on 5th May, 2015].
 B. Adzu et al., Anti-inflammatory and antinociceptive effects of Sphaeranthus senegalensis, J. Ethnopharmacol. 84 (2003) 169–173.
 M.A. Alam et al., Antinociceptive and anti-inflammatory properties of Ruellia tuberosa, Pharm. Biol. 47 (3) (2009) 209-214.
 M.I. Ezeja et al., Anti-inflammatory and Antioxidant Activities of the Methanolic Leaf Extract of Cissus aralioides, Am. J. Pharmacol. Sci. 3 (2015) 1-6.
 F.F. Benzie, J.J. Strain, Ferric reducing/Antioxidant power Assay: Direct measure of total antioxidant activity of biological fluids and modified version for simultaneous measurement of total antioxidant power and ascorbic acid concentration, Methods Enzymol. 299 (1999).
 S.O. Onoja et al., Antioxidant, anti-inflammatory and antinociceptive activities of methanolic extract of Justicia secunda Vahl leaf, Alex. J. Med. (2016) in press. http: /dx. doi. org/10. 1016/j. ajme. 2016. 06. 001.
 F. C Vilela et al., Anti-inflammatory and antipyretic effects of Sonchus oleraceus in rats, J. Ethnopharmacol. 127 (2010) 737–741.
 I.C. Obidike et al., The anti-inflammatory and antinociceptive properties of the chloroform fraction from Phyllanthus niruri plant is mediated via the peripheral nervous system, J. Diet. Suppl. 7 (4) (2010) 341-350.
 M.S. Brandão et al., Antinociceptive effect of lecythis pisonis camb. (lecythidaceae) in models of acute pain in mice, J. Ethnopharmacol. 146 (2013) 180-186.
 A.O.T. Ashafa et al., Evaluation of aqueous extract of Felicia muricata leaves for anti-inflammatory, antinociceptive, and antipyretic activities, Pharm. Biol. 48(9) (2010) 994-1001.