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Effects of Glycyrrhiza glabra, Mentha piperita and their Blend Teas Infusion on Serum Lipids of Wistar Rats

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Abstract:

The aim of this study was to demonstrate the effects of Glycyrrhiza glabra, Mentha piperita and their blend teas on serum lipids of Wistar rats. The animals were divided into control group (CG) and nine treated groups: P1, P3, P5 treated with peppermint tea; L1, L3, L5 treated with Licorice tea and P+L1, P+L3, P+L5 treated with blended peppermint and licorice tea of 10 mg/kg.BW/ml, 30 mg/kg.BW/ml and 50 mg/kg.BW/ml concentrations respectively. The teas were administered orally once in a day for 30 days. P3, P5; L3, L5 and P+L3, P+L5 animals showed significant decrease in triglycerides and total cholesterol and slight increase in HDL-c levels. The levels of LDL-c decreased in the treated groups compared to control group. The results suggested that supplementation with peppermint; licorice and their blend tea extracts can reduce the serum concentrations of cholesterol, triglycerides and LDL.

Info:

Periodical:
International Journal of Pharmacology, Phytochemistry and Ethnomedicine (Volume 5)
Pages:
18-24
Citation:
O. R. Akinseye, "Effects of Glycyrrhiza glabra, Mentha piperita and their Blend Teas Infusion on Serum Lipids of Wistar Rats", International Journal of Pharmacology, Phytochemistry and Ethnomedicine, Vol. 5, pp. 18-24, 2016
Online since:
October 2016
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[1] ICW Arts, PCH Hollman, Polyphones and disease risk in epidemiologic studies, Am J Clin Nutr. 81 (2005) 317–325.

[2] M. Akdogan et al., Investigation of biochemical and histopathological effects of Mentha piperita L. and Mentha spicata L. on kidney tissue in rats, HumExp Toxicol. 22(4) (2003) 213-219.

[3] O. Benavente-Garcia et al., Uses and properties of Citrus flavonoids, J. Agric. Food Chem. 45 (1997) 4505-4515.

[4] S.R. Chanda, Daveet. In vitro models for antioxidant activity evaluation and some medicinal plants possessing antioxidant properties: An overview, Afr J Microbiol Res. 3(13) (2009) 981-996.

[5] YC Chung et al., Antioxidative activity and safety of the 50% ethanol extract from red bean fermented by Bacillus subtilis IMR-NK1, J. Agric. Food Chem. 50 (2002) 2454-(2058).

[6] L.E.R. Cortez, E. Jacomosi, D.A.G. Cortez, Levantamento das plantas medicinais utilizadas na medicina popular de Umuarama, PR, Arq Cien. Saúde UNIPAR. 3(2) (1999) 97- 104.

[7] B. Fuhrman et al., Licorice extract and its major polyphenol glabridin protect low- density lipoprotein against lipid peroxidation: in vitro and in vivo studies in humans and in atherosclerotic lipoprotein E- deficient mice, Am. J. Clin. Nutr. 66 (1997).

[8] T Fukai et al., Preliminaryevaluation of antinephritis and radical scavenging activitiesof glabridin from Glycyrrhizaglabra, Fitoterapia. 74 (2003) 624-629.

[9] A. Gogia, P.K. Agarwal, Metabolic syndrome, Indian J Med Sci. 60(2) (2006) 72-81.

[10] R. Johnson et al., Use of the friedewald formula to estimate LDL-cholesterol in patients with chronic renal failure on dialysis, Clin Chem. 43 (1997) 2183-2184.

[11] N.Z. Johari et al., Acute toxicity and metabolomics analysis of hypocholesterolemic effect of Mentha piperita aqueous extract in Wistar rats, Int J Appl Res Natur Prod. 8(1) (2005) 1-11.

[12] D.C. Luadicina, L.J. Marnett, Enhancement of hydro peroxide dependent lipid peroxidation in rat liver microsomes by ascorbic acid, Arch Biochem Biophys. 278 (1990) 73–80.

[13] Y.M. Li et al., Effects of tea polyphenols on hepatic fibrosis inrats with alcoholic liver disease, HepatobiliaryPancreat Dis Int. 3 (2004) 577–579.

[14] C. Lorenzo et al., Trend in the prevalence of the metabolic syndrome and its impact on cardiovascular disease incidence: the San Antonio Heart Study, Diabetes Care. 29(3) (2006) 625-630.

[15] M. Lu et al., Muscle RelaxingActivity of Hyssopus officinalis Essential Oil on Isolated Intestinal Preparations, Plant. Med. 10(1055) (2002) 213-216.

[16] N. Mimica-Dukic et al., Antimicrobial and antioxidant activities of three Mentha species essential oils, Planta Med. 69(5) (2003) 413-419.

[17] S. Muruganandan et al., Effect of mangiferin on hyperglycemia and atherogenicity in streptozotocin diabetic rats, J Ethnopharmacol. 97 (2005) 497-501.

[18] M. Romero-Jimenez et al., Genotoxicity and anti-genotoxicity of some traditional medicinal herbs, Mutat Res. 1(1-2) (2005) 147-55.

[19] T. Song, S.O. Lee, Soy protein with or without isoflavones, soy germ and soy germ extract, and daidzein lessen cholesterol levels in golden Syrian hamsters, Exp Biol Med. 228(9) (2003) 1063-1068.

[20] P.L. Teissedre, A.L. Waterhouse, Inhibition of oxidation of human low-density lipoproteins by phenolic substances in different essential oils varieties, J Agric Food Chem. 48 (2000) 3801–3805.

[21] M. Toghyani et al., Growth performance, serum biochemistry and blood hematology of broiler chicks fed different levels of black seed (Nigella sativa) and peppermint (Mentha piperita), Livest Sci. 129 (2010) 173-178.

[22] J. Vakkilainen et al., Endothelial Dysfunction in Men With Small LDL Particles, Clin Invest Reports. 102(7) (2000) 716-721.

[23] Z.Y. Wang, D.W. Nixon, Licorice and cancer, Nutr. Cancer. 39 (2001) 1-11.

[24] A.H. Willa, M.J. Quiñones, Role of endothelial dysfunction in insulin resistence, Am J Cardiol. 92 (2003) 101-117.

[25] H. Yki-Järvinen, Insulin resistance and endothelial dysfunction. Best Practice and Ressearch, Clinical Endocrinology and Metabolism. 17 (2003) 411- 430.

[26] J.F. Young et al., Ascorbic acid, alpha-tocopherol, and oregano supplements reduce stress-induced deterioration of chicken meat quality, Poult Sci. 82 (2003) 1343–1351.

[27] Y. Zou, Y. Lu, D. Wei, Hypocholesterolemic effects of a flavonoid-rich extract of Hypericum perforatum L. in rats fed a cholesterol-rich diet, J Agric Food Chem. 7 (2005) 2462-2466.

[28] P. Veeru1, PK Mishra and M Mishra. Screening of medicinal plant extracts for antioxidant Activity, J Med Plant Res. 3(8) (2009) 608-612.

[29] D. Satheeshkumar, A. Kottai Muthu, R. Manavalan, Antioxidant potential of various extracts from whole plant of Ionidium suffruticosum (Ging), Res. J. Pharm., Biol. Chem. Sci. 2(3) (2011) 286-293.

[30] A. Scalbert et al., Absorption and metabolism of polyphenols in the gut and impact on health, Biomed Pharmacother. 56 (2002) 276–282.

[31] G.E. Trease, M.C. Evans, Textbook of Pharmacognosy, 12th edition, Balliere Tindall, 1983, pp.343-383.

[32] C.K. Kokate, Practical Pharmacognosy, Vallabh Prakashan, New Delhi, 1994, pp.107-111.

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Cited By:

[1] F. Jafari, M. Jafari, A. Moghadam, S. Emami, T. Jamialahmadi, A. Mohammadpour, A. Sahebkar, Natural Products and Human Diseases, Vol. 1328, p. 385, 2021

DOI: https://doi.org/10.1007/978-3-030-73234-9_25

[2] F. Jafari, M. Jafari, A. Moghadam, S. Emami, T. Jamialahmadi, A. Mohammadpour, A. Sahebkar, Natural Products and Human Diseases, Vol. 1328, p. 385, 2021

DOI: https://doi.org/10.1007/978-3-030-73234-9_25

[3] F. Jafari, M. Jafari, A. Moghadam, S. Emami, T. Jamialahmadi, A. Mohammadpour, A. Sahebkar, Natural Products and Human Diseases, Vol. 1328, p. 385, 2021

DOI: https://doi.org/10.1007/978-3-030-73234-9_25