This study describes the specific features of the distribution of Romanian patients with pancreatic neoplasm. The analysis was made on 188 patients from Clinical Emergency Hospital “Sf. Spiridon, Iasi”, Romania, all with solid form of pancreatic cancer. Moreover, the distribution by age, gender, tumor location in the pancreas or by the stages from the TNM system was analyzed and compared with other studies from other countries. Thus, in our sample the median age was 65 years old. In addition, 53% of the patients had rural origin and 47% urban origin. Also, regarding the pancreatic tumor location, by far the most frequent was the cephalic location (75%). Moreover, when we study the distribution by presence of metastases at the time of diagnosis, we observed that 62.1% are located in the liver and 21.2% into the peritoneum. In addition, when we staged the ductal adenocarcinoma of the pancreas according to the TNM (tumour grade, nodal status and metastases) system, where T1-T3 constitutes a resectable tumour and T4 indicates an unresectable tumour, we found that group T4 stage tumor predominated (63.8%), while in regards to the regional lymph nodes (e.g. N in TNM classification) we observed that in an overwhelming proportion Nx stage predominates (88.6%). Moreover, no distant metastasis was found in 63% of patients, by using M in TNM classification. In this way, a better understanding of the specific characteristics for the affected population could prove to be extremely important, especially considering the fact during the last decades the development of the surgical methods and techniques for this disorder had no significant impact on the survival rate.
International Journal of Pharmacology, Phytochemistry and Ethnomedicine (Volume 4)
D. Timofte et al., "An Evaluation of the Relative Distribution of Romanian Patients with Pancreatic Neoplasm", International Journal of Pharmacology, Phytochemistry and Ethnomedicine, Vol. 4, pp. 83-89, 2016