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Comparative Study on Phytochemical Composition and In Vitro Radical Scavenging Activity of Ethanolic Extracts of Landolphia lanceolata and Nutraceutical-C24/7

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This study investigated the phytochemical composition and in-vitro radical scavenging activity of ethanolic extracts of Nutraceutical-C24/7 and Landolphia lanceolata fruit. Phytochemical screening of Landolphia lanceolata fruit extract indicated the presence of phenols, flavonoids, saponins, alkaloids, terpenoids, tannins, triterpenoids and steroids. While nutraceutical-C24/7 showed precence of with exception of saponins, terpenoids and triterpenoids. Some of the identified Phytochemicals and vitamins concentrations quantified were higher in Landolphia lanceolata fruit extract than nutraceutical-C24/7 with statistically significant difference (p<0.05) with the former having flavonoids 0.062±0.00mg/ml, phenol 0.097±0.00mg/ml, vitamin C 206±42mg/dL, vitamin B1 54.16±0.00mg/dL and vitamin B2 0.11±0.00mg/dL while, Nutraceutical-C24/7 extract had flavonoid 0.117±0.00mg/ml, phenol 0.032±0.00, vitamin C 102.24±0.00mg/dL, vitamin B1 23.36±0.00mg/dL, and vitamin B2 0.067±0.00mg/dL. The study also showed that at higher concentration, DPPH radical, ferric ion, and hydrogen peroxide the extracts radical scavenging activity increased. The study showed that the extracts scavenging activities at different concentrations had higher percentage inhibition on DPPH radical, reducing power of ferric ion capabilities and reducing composition of hydrogen peroxide indicated that ethanolic extract of Landolphia lanceolata fruits showed statistically significant different (p<0.05) when compared with ethanolic extract of Nutraceutical-C24/7. Standard vitamin C percentage inhibition for DPPH radical compared well with that of Landolphia lanceolata fruit extract at higher concentration with no statistical significant different (p>0.05). The indigenous functional food Landolphia lanceolata fruit can be concluded to be a good antioxidant that can scavenge, inhibit and quench free radicals. This suggests that Landolphia lanceolata may be considered a good source and alternative antioxidant for developing countries like Nigeria.


International Journal of Pharmacology, Phytochemistry and Ethnomedicine (Volume 10)
C. C. Nweze et al., "Comparative Study on Phytochemical Composition and In Vitro Radical Scavenging Activity of Ethanolic Extracts of Landolphia lanceolata and Nutraceutical-C24/7", International Journal of Pharmacology, Phytochemistry and Ethnomedicine, Vol. 10, pp. 36-44, 2018
Online since:
July 2018

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